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Browse Items (19 total)

  • Tags: Clinical Trial

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Creator: WHO Solidarity Trial Consortium
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-02
Description: World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a — in patients hospitalized with coronavirus disease 2019 (Covid-19).

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Creator: Boulware, David R., Matthew F. Pullen, Ananta S. Bangdiwala, Katelyn A. Pastick, Sarah M. Lofgren, Elizabeth C. Okafor, Caleb P. Skipper, Alanna A. Nascene, Melanie R. Nicol, Mahsa Abassi, Nicole W. Engen, Matthew P. Cheng, Derek LaBar, Sylvain A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-06
Description: This reports on a randomized, double-blind, placebo-controlled trial across the United States and parts of Canada testing hydroxychloroquine as postexposure prophylaxis.

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Creator: National Institute of Allergy and Infectious Diseases (NIAID)
Subject: Research
Item Type: Hyperlink
Date Last Updated: 2020-05-07
Description: This study is an adaptive, randomized, double-blind, placebo-controlled trial to evaluate the safety and efficacy of novel therapeutic agents in hospitalized adults diagnosed with COVID-19. The study is a multicenter trial that will be conducted in…

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Creator: the ACTT-1 Study Group Members
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2020-05-22
Description: Discussing "a double-blind, randomized, placebo-controlled trial of intravenous remdesivir in adults hospitalized with Covid-19 with evidence of lower respiratory tract involvement."

Creator: Dean, Natalie E., Pierre-Stéphane Gsell, Ron Brookmeyer, Forrest W. Crawford, Christl A. Donnelly, Susan S. Ellenberg, Thomas R. Fleming, M. Elizabeth Halloran, Peter Horby, Thomas Jaki, Philip R. Krause, Ira M. Longini, Sabue Mulangu, Jean-Jacques…
Subject: Emergency Management
Item Type: Publication
Date Last Updated: 2020-04-02
Description: Conducting trials of novel interventions during infectious disease emergencies, such as the ongoing Covid-19 pandemic, is increasingly recognized as important for determining the efficacy of potential vaccines and therapies.

Creator: Fallah MP, Skrip LA.
Subject: Research
Item Type: Publication
Date Last Updated: 2019-01-24
Description: This article reviews the testing of Ebola therapies during the outbreak.

Creator: Mbala-Kingebeni P, Aziza A, Di Paola N, Wiley MR, Makiala-Mandanda S, Caviness K, Pratt CB, Ladner JT, Kugelman JR, Prieto K, Chitty JA, Larson PA, Beitzel B, Ayouba A, Vidal N, Karhemere S, Diop M, Diagne MM, Faye M, Faye O, Aruna A, Nsio J, Mulangu…
Subject: Research
Item Type: Publication
Date Last Updated: 2019-04-15
Description: The real-time generation of information about pathogen genomes has become a vital goal for transmission analysis and characterisation in rapid outbreak responses. In response to the recently established genomic capacity in the Democratic Republic of…

Creator: Anise N Happi, Chinedu A Ugwu, Christian T Happi
Subject: Research
Item Type: Publication
Date Last Updated: 2019-04-15
Description: This article discusses how "real-time genomic viral sequencing and surveillance of human populations represents a simple and cost-effective method of mitigating outbreaks in countries and locations that are most at risk of infectious disease…