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Read current official WHO and CDC news updates, listed below in the Newsfeeds section, descending from the most recent on top. See the notices from both organizations mapped globally immediately below.**

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WHO Disease Outbreaks

  • Human infection with avian influenza A (H5N8) – the Russian Fe...
    Fri, 26 Feb 2021
    On 18 February 2021, the National IHR Focal Point for the Russian Federation notified WHO of detection of avian influenza A(H5N8) in seven human clinical specimens. These are the first reported detection of avian influenza A(H5N8) in humans. Positive clinical specimens were collected from poultry farm workers who participated in a response operation to contain an avian influenza A(H5N8) outbreak detected in a poultry farm in Astrakhan Oblast in the Russian Federation. The laboratory confirmation of the seven specimens were performed by the State Research Centre for Virology and Biotechnology VECTOR (WHO H5 Reference Laboratory). The age of seven positive cases ranged between 29 to 60 years and five were female.

    Between 3 and 11 December, a total of 101 000 of 900 000 egg laying hens on the farm died. This high mortality rate prompted an investigation. Samples were collected from these birds and an initial detection of avian influenza A(H5N8) was performed by the Russian regional veterinary laboratory. On 11 December, the outbreak was confirmed by the World Organisation for Animal Health (OIE) Reference laboratory, and the Federal Centre for Animal Health (FGBI-ARRIAH), in Vladimir, the Russian Federation. Outbreak containment operations started immediately and continued for several days due to the large size of the poultry farm.
  • Ebola virus disease – Guinea...
    Wed, 17 Feb 2021
    On 14 February 2021, the Ministry of Health (MoH) of Guinea informed WHO of a cluster of Ebola Virus
  • Rift Valley fever – Kenya...
    Fri, 12 Feb 2021
    Rift Valley fever (RVF) has been reported in Kenya in humans in Isiolo and Mandera counties and in

CDC Travel Notices:

 

Click here to search for travel related diseases by country.

The Travel Clinical Assistant (TCA) is by the Georgia Department of Health.

 

CDC Morbidity and Mortality Weekly Report (MMWR):

 

Current Journal Updates

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Clinical Infectious Diseases Journal

This list includes items from the latest issue of the Clinical Infectious Diseases Journal.

  • Reply to Yamaoka, et al...
    Thu, 08 Apr 2021
    To the Editor—We thank Yamaoka and colleagues for their interest and comments on our paper [1]. Yamaoka et al point out that there are cross-reactivities of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) full-length nucleoprotein (FL-NP) with antibodies to other common human coronaviruses (HCoVs), which may cause false positive results in serological assays. They propose to use a truncated version of NP lacking the N-terminal (ΔNP) to detect SARS-CoV-2 antibodies.
  • Infectious Diseases Society of America Guidance on the Treatment ...
    Thu, 08 Apr 2021
    Abstract
    Background
    Antimicrobial-resistant infections are commonly encountered in US hospitals and result in significant morbidity and mortality. This guidance document provides recommendations for the treatment of infections caused by extended-spectrum β-lactamase–producing Enterobacterales (ESBL-E), carbapenem-resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with difficult-to-treat resistance (DTR-P. aeruginosa).
    Methods
    A panel of 6 infectious diseases specialists with expertise in managing antimicrobial-resistant infections formulated common questions regarding the treatment of ESBL-E, CRE, and DTR-P. aeruginosa infections. Based on review of the published literature and clinical experience, the panel provide recommendations and associated rationale for each recommendation. Because of significant differences in the molecular epidemiology of resistance and the availability of specific anti-infective agents globally, this document focuses on treatment of antimicrobial-resistant infections in the United States.
    Results
    Approaches to empiric treatment selection, duration of therapy, and other management considerations are briefly discussed. The majority of guidance focuses on preferred and alternative treatment recommendations for antimicrobial-resistant infections, assuming that the causative organism has been identified and antibiotic susceptibility testing results are known. Treatment recommendations apply to both adults and children.
    Conclusions
    The field of antimicrobial resistance is dynamic and rapidly evolving, and the treatment of antimicrobial-resistant infections will continue to challenge clinicians. This guidance document is current as of 17 September 2020. Updates to this guidance document will occur periodically as new data emerge. Furthermore, the panel will expand recommendations to include other problematic gram-negative pathogens in future versions. The most current version of the guidance including the date of publication can be found at www.idsociety.org/practice-guideline/amr-guidance/.

  • An Uncommon Cause of Chronic Cough...
    Thu, 08 Apr 2021
    A 48-year-old female with no past medical history presented to the emergency department in June 2020 with a 6-month history of productive cough associated with nausea, vomiting, and 20-kg weight loss. She had no other symptoms. She lived in mainland France for 20 years, and had been living in Martinique for the past 9 years. She works as a caregiver, and her husband is a goat breeder. She has a dog and a cat. At clinical examination, the patient had no fever and no evidence of respiratory distress. She had a normal oxygen saturation. Heart and lung auscultation were unremarkable. The rest of the examination was normal. The peripheral white blood cell count was 5.84 G/L, of which 0.42 G/L were eosinophils. A mild normochromic normocytic anemia (hemoglobin, 11.6 g/dL) was found. There was no thrombocytopenia, and the C-reactive protein level was <3 mg/L. Liver and kidney function markers were also within normal ranges. Computed tomography of the chest revealed a ground-glass opacity at the base of the middle lobe (Figure 1). A bronchoscopy was performed. Bronchial mucosa appeared to be slightly inflamed with yellowish mucous secretions. During exploration of the right basal pyramid, the endoscopist found and removed a Y-shaped whitish–red motile body. The entire structure was sent to the parasitology laboratory for further identification (Figure 2).

Listen: New England Journal of Medicine

The New England Journal of Medicine is a weekly general medicine journal, and this audio news feed presents interviews with specialists.

  • Vaccine Successes and Vaccine Adverse Events...
    Wed, 14 Apr 2021
    Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Vaccine Successes and Vaccine Adverse Events. N Engl J Med 2021;384:e70.
  • NEJM Interview: Dr. Andrew Ryan on new legislation to prevent pat...
    Wed, 14 Apr 2021
    Dr. Andrew Ryan is the director of the Center for Evaluating Health Reform at the University of Michigan School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. K.R. Chhabra, E. Fuse Brown, and A.M. Ryan. No More Surprises — New Legislation on Out-of-Network Billing. N Engl J Med 2021;384:1381-1383.
  • Antibody Responses to Natural Infection and Vaccination...
    Wed, 07 Apr 2021
    Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Antibody Responses to Natural Infection and Vaccination. N Engl J Med 2021;384:e65.

Emerging Infectious Diseases Journal:

This list contains articles published online ahead of print.

 

Center for Infectious Disease Research and Policy:

News from the University of Minnesota Center for Infectious Disease Research and Policy (CIDRAP).

Johns Hopkins Medicine RSS Feed:

Johns Hopkins Medicine science and medical news.

  • Amoeba Biology Reveals Potential Treatment Target for Lung Diseas...
    Tue, 13 Apr 2021
    Newswise image In a series of experiments that began with amoebas -- single-celled organisms that extend podlike appendages to move around -- Johns Hopkins Medicine scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.
  • Lifetime Monitoring Following Infant Cardiac Surgery May Reduce F...
    Tue, 13 Apr 2021
    Newswise imageIn a medical records study covering thousands of children, a U.S.-Canadian team led by researchers at Johns Hopkins Medicine concludes that while surgery to correct congenital heart disease (CHD) within 10 years after birth may restore young hearts to healthy function, it also may be associated with an increased risk of hypertension -- high blood pressure -- within a few months or years after surgery.
  • Johns Hopkins Medicine Establishes Center Thanks to Gift from Mer...
    Wed, 07 Apr 2021
    Thanks to a gift from the Merkin Family Foundation, Johns Hopkins Medicine today announced plans for a new virtual center to study peripheral neuropathy, a debilitating nerve disorder that affects some 20 million people in the United States. The gift will also fund the development of innovative nerve regenerative therapies to combat the disorder.

American Journal of Infection Control:

RSS feed including 'the latest published articles, both published in an issue and published as Articles in Press.'

  • Methodology Minute: A statistical test primer for infection prev...
    2021-04-16
    Selecting the appropriate statistical tests for data analysis is a critical skill for the infection preventionist (IP), both for analyzing their own data as well as evaluating the scientific literature methodology. Obtaining results from data analyses has never been easier thanks to computational improvements, but the interpretation of results relies on a keen awareness that the approach was sound. The purpose of this primer is to introduce the infection preventionist to the ideas behind hypothesis testing with a focus on statistical test selection.
  • A Retrospective Comparison of Guidelines to Assess Hospital-diag...
    2021-04-16
    The problem of nursing home (NH) residents receiving inappropriate antibiotic treatments for urinary tract infection (UTI) is well documented.1,2 However, little evidence exists about the accuracy of hospital UTI diagnosis and treatment of NH residents who were admitted to the hospital and then transferred back to the NH.3 Due to the widespread presence of asymptomatic bacteriuria (ASB) in NH residents, UTIs are diagnosed differently in this population than they are in community-dwelling adults.
  • A Comprehensive Approach to Ending an Outbreak of Rare blaOXA-72...
    2021-04-08
    We identified a cluster of extensively drug-resistant, carbapenemase gene-positive, carbapenem-resistant Acinetobacter baumannii (CP-CRAB) at a teaching hospital in Kansas City. Extensively drug-resistant CRAB was identified from eight patients and 3% of environmental cultures. We used patient cohorting and targeted environmental disinfection to stop transmission. After implementation of these measures, no additional cases were identified.


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