Browse Items (681 total)

• Select Agent Regulatory Challenges in a Patient Care Setting: Review and Recommendations

  Tags Biosafety, Patient Care, R-Res&Pub
  Creator: Basic and Translational State of the Science Working Group of the National Emerging Special Pathogens Training and Education Center Special Pathogens Research Network
  Subject: Treatment & Care
  Item Type: Publication
  Date Last Updated: 2023-12-06
  Description: The Federal Select Agent Program ensures the safe and secure possession, use, and transfer of biological select agents and toxins through the select agent regulations (42 CFR §73, 7 CFR §331, and 9 CFR §121). These regulations are primarily written…

• Emergency Use Authorization

  Tags Emergency Management, R-Res&Pub, Research, Therapeutics
  Creator: FDA
  Subject: Research
  Item Type: Hyperlink
  Date Last Updated: 2023-05-12
  Description: The Emergency Use Authorization (EUA) authority allows FDA to help strengthen the nation’s public health protections against chemical, biological, radiological, and nuclear (CBRN) threats including infectious diseases, by facilitating the…

• Investigational New Drug (IND) Application

  Tags R-Res&Pub, Research, Therapeutics
  Creator: FDA
  Subject: Research
  Item Type: Hyperlink
  Date Last Updated: 2022-07-20
  Description: Current Federal law requires that a drug be the subject of an approved marketing application before it is transported or distributed across state lines. Because a sponsor will probably want to ship the investigational drug to clinical investigators…
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  Monkeypox: A Contemporary Review for Healthcare Professionals

  Tags Emergency Management, Mpox, R-Res&Pub, Treatment and Care
  Creator: Boghuma K Titanji, Bryan Tegomoh, Saman Nematollahi, Michael Konomos, Prathit A Kulkarni
  Subject: General
  Item Type: Publication
  Date Last Updated: 2022-06-23
  Description: We present in this review an updated overview of monkeypox for healthcare professionals in the context of the ongoing outbreaks around the world.

• Evaluation and comparison of three virucidal agents on inactivation of Nipah virus

  Tags Nipah (NiV), R-Lab, R-Res&Pub
  Creator: Huang, Yi, Shuqi Xiao, Donglin Song, and Zhiming Yuan.
  Subject: Laboratory
  Item Type: Publication
  Date Last Updated: 2022-07-05
  Description: Modern human activity is profoundly changing our relationship with microorganisms with the startling rise in the rate of emerging infectious diseases. Nipah virus together with Ebola virus and SARS-CoV-2 are prominent examples.

• Using healthcare-seeking behaviour to estimate the number of Nipah outbreaks missed by hospital-based surveillance in Bangladesh

  Tags Nipah (NiV), R-EM, R-Res&Pub
  Creator: Hegde, S. T., H. Salje, H. M. S. Sazzad, M. J. Hossain, M. Rahman, P. Daszak, J. D. Klena, S. T. Nichol, S. P. Luby, and E. S. Gurley.
  Subject: Laboratory
  Item Type: Publication
  Date Last Updated: 2019-08-01
  Description: Understanding the true burden of emergent diseases is critical for assessing public-health impact. However, surveillance often relies on hospital systems that only capture a minority of cases. We use the example of Nipah-virus infection in…

• Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study

  Tags Nipah (NiV), R-Res&Pub, R-T&C, Trial
  Creator: Playford, E. G., T. Munro, S. M. Mahler, S. Elliott, M. Gerometta, K. L. Hoger, M. L. Jones, P. Griffin, K. D. Lynch, H. Carroll, D. El Saadi, M. E. Gilmour, B. Hughes, K. Hughes, E. Huang, C. de Bakker, R. Klein, M. G. Scher, I. L. Smith, L. F.…
  Subject: Laboratory
  Item Type: Publication
  Date Last Updated: 2020-04
  Description: The monoclonal antibody m102.4 is a potent, fully human antibody that neutralises Hendra and Nipah viruses in vitro and in vivo. We aimed to investigate the safety, tolerability, pharmacokinetics, and immunogenicity of m102.4 in healthy adults.

• Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge

  Tags Nipah (NiV), R-Res&Pub, R-T&C, Remdesivir
  Creator: Michael K. Lo, Friederike Feldmann, Joy M. Gary, Robert Jordan, Roy Bannister, Jacqueline Cronin, Nishi R. Patel, John D. Klena, Stuart T. Nichol, Tomas Cihlar, Sherif R. Zaki, Heinz Feldmann, Christina F. Spiropoulou, and Emmie de Wit.
  Subject: Laboratory
  Item Type: Publication
  Date Last Updated: 2019-05-29
  Description: Nipah virus is an emerging pathogen in the Paramyxoviridae family. Upon transmission of Nipah virus from its natural reservoir, Pteropus spp. fruit bats, to humans, it causes respiratory and neurological disease with a case-fatality rate about 70%.

• Collaborative Institutional Training Initiative (CITI Program)

  Tags Laboratory, Protocol, R-Lab, R-Res&Pub, Research, Training
  Creator: CITI Program
  Subject: Laboratory
  Item Type: Hyperlink
  Date Last Updated: 2022
  Description: The Collaborative Institutional Training Initiative (CITI Program) is dedicated to serving the training needs of colleges and universities, healthcare institutions, technology and research organizations, and governmental agencies, as they foster…

• CDC Laboratory Training

  Tags Biosafety, Laboratory, Occupational Health, R-Lab, R-Res&Pub, Training
  Creator: CDC
  Subject: Laboratory
  Item Type: Hyperlink
  Date Last Updated: 2022-06-29
  Description: This page includes a selection of different laboratory trainings.