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Browse Items (103 total)

  • Tags: Therapeutics

Creator: Furtado, Remo H. M., Otavio Berwanger, Henrique A. Fonseca, Thiago D. Corrêa, Leonardo R. Ferraz, Maura G. Lapa, Fernando G. Zampieri, Viviane C. Veiga, Luciano C. P. Azevedo, Regis G. Rosa, Renato D. Lopes, Alvaro Avezum, Airton L. O. Manoel,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-08
Description: The efficacy and safety of azithromycin in the treatment of COVID-19 remain uncertain. We assessed whether adding azithromycin to standard of care, which included hydroxychloroquine, would improve clinical outcomes of patients admitted to the…

Creator: Boulware, David R., Matthew F. Pullen, Ananta S. Bangdiwala, Katelyn A. Pastick, Sarah M. Lofgren, Elizabeth C. Okafor, Caleb P. Skipper, Alanna A. Nascene, Melanie R. Nicol, Mahsa Abassi, Nicole W. Engen, Matthew P. Cheng, Derek LaBar, Sylvain A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-06
Description: This reports on a randomized, double-blind, placebo-controlled trial across the United States and parts of Canada testing hydroxychloroquine as postexposure prophylaxis.

Creator: Normand, Sharon-Lise T.
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2020-07-21
Description: In a platform trial, patients with a single disease are randomly assigned to a group of different therapies on the basis of a decision algorithm to determine whether any therapy has benefit.

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Creator: The RECOVERY Collaborative Group.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-07-17
Description: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death.

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Creator: CDC
Subject: Training and Exercises
Item Type: Exercise
Date Last Updated: 2020-06-26
Description: Training materials on: Clinical Care & Infection Control, Personal Protective Equipment (PPE), Nonpharmaceutical Interventions (NPIs), Emergency Preparedness and Response, and Additional Topics.

Creator: Iversen, Patrick L., Christopher D. Kane, Xiankun Zeng, Rekha G. Panchal, Travis K. Warren, Sheli R. Radoshitzky, Jens H. Kuhn, Rajini R. Mudhasani, Christopher L. Cooper, Amy C. Shurtleff, Farooq Nasar, Melek M. E. Sunay, Allen J. Duplantier, Brett…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-06-18
Description: The PALM trial in the Democratic Republic of the Congo identified a statistically significant survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute Ebola virus disease; however, substantial gaps remain in improving…

Creator: Tedder, Richard S., and Malcolm G. Semple.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-06-15
Description: We read with considerable interest the Comment from Long Chen and colleagues about the potential use of convalescent plasma for the treatment of COVID-19.

Creator: Meng, Xianmin, Yun Ling, Li Zhang, Qian Zhang, Ping Dong, Tongyu Zhu, and Hongzhou Lu.
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2020-06-11
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become a serious public health threat to the whole world, and the number of infected is still rising dramatically at this moment. Several studies have confirmed that cytokine…

Creator: Cohen, Myron S.
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2020-06-03
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), has generated a worldwide pandemic. The interruption of its spread depends on a combination of pharmacologic and nonpharmacologic…