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Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks

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Title

Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks

Description

Conducting trials of novel interventions during infectious disease emergencies, such as the ongoing Covid-19 pandemic, is increasingly recognized as important for determining the efficacy of potential vaccines and therapies.

Date

2020-04-02

Citation

Dean, Natalie E., Pierre-Stéphane Gsell, Ron Brookmeyer, Forrest W. Crawford, Christl A. Donnelly, Susan S. Ellenberg, Thomas R. Fleming, M. Elizabeth Halloran, Peter Horby, Thomas Jaki, Philip R. Krause, Ira M. Longini, Sabue Mulangu, Jean-Jacques Muyembe-Tamfum, Martha C. Nason, Peter G. Smith, Rui Wang, Ana M. Henao-Restrepo, and Victor De Gruttola. 2020. "Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks." New England Journal of Medicine 382 (14):1366-9.

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Free online on NEJM.

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