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Parcourir les contenus (629 total)
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Créateur: Khanna, S., and C. S. Kraft.
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2021-04-13
Description: The COVID-19 pandemic has changed the way we practice medicine and lead our lives. In addition to pulmonary symptoms; COVID-19 as a syndrome has multisystemic involvement including frequent gastrointestinal symptoms such as diarrhea. -
Créateur: Boulanger, M., E. Molina, K. Wang, T. Kickler, Y. Xu, and B. T. Garibaldi.
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2021-03-31
Description: Cytokines seen in severe COVID-19 are associated with proliferation, differentiation, and survival of plasma cells. Plasma cells are not routinely found in peripheral blood, though may produce virus-neutralizing antibodies in COVID-19 later in the… -
Créateur: Adelman, M. W., D. R. Bhamidipati, A. C. Hernandez-Romieu, A. Babiker, M. H. Woodworth, C. Robichaux, D. J. Murphy, S. C. Auld, C. S. Kraft, and J. T. Jacob.
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2021-04-06
Description: Hospitalized patients, particularly those who are critically ill, are at risk for ‘secondary’ infections(1, 2). Initial reports of patients hospitalized with COVID-19 indicate that 10-33% develop bacterial pneumonia(3, 4) and 2-6% develop bloodstream… -
Créateur: Wiley, Z., K. Ross-Driscoll, Z. Wang, L. Smothers, A. K. Mehta, and R. E. Patzer.
Sujet: Treatment & Care
Type d'élément: Publication
Date de la dernière mise à jour: 2021-04-02
Description: Since the introduction of remdesivir and dexamethasone for severe COVID-19 treatment, few large multi-hospital system US studies have described clinical characteristics and outcomes of minority COVID-19 patients who present to the emergency… -
Créateur: Leshem, Eyal, and Benjamin Alan Lopman.
Sujet: Infection Control
Type d'élément: Publication
Date de la dernière mise à jour: 2021-04-23
Description: Vaccines act by two broad main mechanisms. They can block infection occurring entirely or they can halt the progression to symptoms after infection occurs. -
Créateur: Rosas, Ivan O., Norbert Bräu, Michael Waters, Ronaldo C. Go, Bradley D. Hunter, Sanjay Bhagani, Daniel Skiest, Mariam S. Aziz, Nichola Cooper, Ivor S. Douglas, Sinisa Savic, Taryn Youngstein, Lorenzo Del Sorbo, Antonio Cubillo Gracian, David J. De La…
Sujet: Treatment & Care
Type d'élément: Publication
Date de la dernière mise à jour: 2021-04-22
Description: Coronavirus disease 2019 (Covid-19) is associated with immune dysregulation and hyperinflammation, including elevated interleukin-6 levels. The use of tocilizumab, a monoclonal antibody against the interleukin-6 receptor, has resulted in better… -
Créateur: Scully, Marie, Deepak Singh, Robert Lown, Anthony Poles, Tom Solomon, Marcel Levi, David Goldblatt, Pavel Kotoucek, William Thomas, and William Lester.
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2021-04-16
Description: The mainstay of control of the coronavirus disease 2019 (Covid-19) pandemic is vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Within a year, several vaccines have been developed and millions of doses delivered.… -
Créateur: Chappell, Keith J., Francesca L. Mordant, Zheyi Li, Danushka K. Wijesundara, Paula Ellenberg, Julia A. Lackenby, Stacey T. M. Cheung, Naphak Modhiran, Michael S. Avumegah, Christina L. Henderson, Kym Hoger, Paul Griffin, Jillian Bennet, Luca Hensen,…
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2021-04-19
Description: Given the scale of the ongoing COVID-19 pandemic, the development of vaccines based on different platforms is essential, particularly in light of emerging viral variants, the absence of information on vaccine-induced immune durability, and potential… -
Créateur: Goepfert, Paul A., Bo Fu, Anne-Laure Chabanon, Matthew I. Bonaparte, Matthew G. Davis, Brandon J. Essink, Ian Frank, Owen Haney, Helene Janosczyk, Michael C. Keefer, Marguerite Koutsoukos, Murray A. Kimmel, Roger Masotti, Stephen J. Savarino, Lode…
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2021-04-19
Description: CoV2 preS dTM is a stabilised pre-fusion spike protein vaccine produced in a baculovirus expression system being developed against SARS-CoV-2. We present interim safety and immunogenicity results of the first-in-human study of the CoV2 preS dTM… -
Créateur: Hacisuleyman, Ezgi, Caryn Hale, Yuhki Saito, Nathalie E. Blachere, Marissa Bergh, Erin G. Conlon, Dennis J. Schaefer-Babajew, Justin DaSilva, Frauke Muecksch, Christian Gaebler, Richard Lifton, Michel C. Nussenzweig, Theodora Hatziioannou, Paul D.…
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2021-04-21
Description: Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 (Pfizer–BioNTech) or mRNA-1273 (Moderna) vaccine at least 2 weeks…