The interplay of SARS-CoV-2 and Clostridioides difficile infection

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Title

The interplay of SARS-CoV-2 and Clostridioides difficile infection

Subject

Description

The COVID-19 pandemic has changed the way we practice medicine and lead our lives. In addition to pulmonary symptoms; COVID-19 as a syndrome has multisystemic involvement including frequent gastrointestinal symptoms such as diarrhea.

Date Last Updated (Year-Month-Day)

2021-04-13

Citation

Khanna, S., and C. S. Kraft. 2021. "The interplay of SARS-CoV-2 and Clostridioides difficile infection." Future Microbiol 16:439-43.

Abstract

The COVID-19 pandemic has changed the way we practice medicine and lead our lives. In addition to pulmonary symptoms; COVID-19 as a syndrome has multisystemic involvement including frequent gastrointestinal symptoms such as diarrhea. Due to microbiome alterations with COVID-19 and frequent antibiotic exposure, COVID-19 can be complicated by Clostridioides difficile infection. Co-infection with these two can be associated with a high risk of complications. Infection control measures in hospitals is enhanced due to the COVID-19 pandemic which in turn appears to reduce the incidence of hospital-acquired infections such as C. difficile infection. Another implication of COVID-19 and its potential transmissibility by stool is microbiome-based therapies. Potential stool donors should be screened COVID-19 symptoms and be tested for COVID-19.

Keywords: COVID-19; Clostridioides difficile; colitis; diarrhea; infection; pandemic.

Accessibility

Free access on Future Medicine.