Browse Items (106 total)

• Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in children in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial

  Tags Ebola, Pediatrics, R-Res&Pub, R-SP, Therapeutics, Vaccine Study, Viral Hemorrhagic Fever
  Creator: Tapia, Milagritos D., Samba O. Sow, Khardiata D. Mbaye, Aliou Thiongane, Birahim P. Ndiaye, Cheikh T. Ndour, Souleymane Mboup, Babajide Keshinro, Thompson N. Kinge, Guy Vernet, Jean Joel Bigna, Stephen Oguche, Kwadwo A. Koram, Kwaku P. Asante,…
  Subject: Research
  Item Type: Publication
  Date Last Updated: 2020-03-19
  Description: During the large 2013–16 Ebola virus outbreak caused by the Zaire Ebola virus, about 20% of cases were reported in children. This study is the first, to our knowledge, to evaluate an Ebola vaccine in children younger than 6 years.

• Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in adults in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial

  Tags Ebola, R-Res&Pub, Therapeutics, Vaccine Study, Viral Hemorrhagic Fever
  Creator: Tapia, Milagritos D., Samba O. Sow, Birahim P. Ndiaye, Khardiata D. Mbaye, Aliou Thiongane, Cheikh T. Ndour, Souleymane Mboup, Julie A. Ake, Babajide Keshinro, Gideon A. Akintunde, Thompson N. Kinge, Guy Vernet, Jean Joel Bigna, Stephen Oguche,…
  Subject: Research
  Item Type: Publication
  Date Last Updated: 2020-03-19
  Description: The 2014 Zaire Ebola virus disease epidemic accelerated vaccine development for the virus.

• Chimpanzee adenovirus type 3 vectored Ebola vaccine: expanding the field

  Tags Ebola, R-Res&Pub, Therapeutics, Vaccine Study, Viral Hemorrhagic Fever
  Creator: Bavari, Sina, and Patrick L. Iversen.
  Subject: Research
  Item Type: Publication
  Date Last Updated: 2020-03-19
  Description: Two phase 2 randomised clinical trials evaluating ChAd3-EBO-Z administered to healthy adults in Cameroon, Mali, Nigeria, and Senegal and healthy children in Mali and Senegal are reported by Milagritos Tapia and colleagues in The Lancet Infectious…
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  Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment

  Tags 2019-nCoV, Coronavirus, COVID-19, R-Res&Pub, Respiratory Pathogen, Therapeutics
  Creator: Wang, Zhenwei, Xiaorong Chen, Yunfei Lu, Feifei Chen, and Wei Zhang.
  Subject: Research
  Item Type: Publication
  Date Last Updated: 2020-03-15
  Description: Pneumonia associated with the 2019 novel coronavirus (2019-nCoV) is continuously and rapidly circulating at present.
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  Bioaerosol sampling for the detection of aerosolized influenza virus

  Tags Airborne Transmission, Flu, Infection Prevention and Control, Influenza, R-Res&Pub, Therapeutics
  Creator: Blachere, Francoise M., William G. Lindsley, James E. Slaven, Brett J. Green, Stacey E. Anderson, Bean T. Chen, and Don H. Beezhold.
  Subject: Research
  Item Type: Publication
  Date Last Updated: 2007-05
  Description: A Collison single-jet nebulizer was used to aerosolize the attenuated FluMist vaccine into a calm-air settling chamber.
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  Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

  Tags Coronavirus, R-Res&Pub, Research, Therapeutics
  Creator: Agostini, Maria, Erica Andres, Amy Sims, Rachel Graham, Timothy Sheahan, Xiaotao Lu, Everett Smith, James Case, Joy Feng, Robert Jordan, Adrian Ray, Tomas Cihlar, Dustin Siegel, Richard Mackman, Michael Clarke, Ralph Baric, and Mark Denison.
  Subject: Research
  Item Type: Publication
  Date Last Updated: 2018-03
  Description: Emerging coronaviruses (CoVs) cause severe disease in humans, but no approved therapeutics are available.
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  Severe 2019-nCoV Remdesivir RCT

  Tags Coronavirus, COVID-19, Laboratory Testing, R-Res&Pub, Therapeutics
  Creator: NIH
  Subject: Research
  Item Type: Hyperlink
  Date Last Updated: 2020-02-10
  Description: In December 2019, Wuhan, in Hubei province, China, became the center of an outbreak of pneumonia of unknown cause. In a short time, Chinese scientists had shared the genome information of a novel coronavirus (2019-nCoV) from these pneumonia patients…
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  Mild/Moderate 2019-nCoV Remdesivir RCT

  Tags Coronavirus, COVID-19, Laboratory Testing, R-Res&Pub, Therapeutics
  Creator: NIH
  Subject: Research
  Item Type: Hyperlink
  Date Last Updated: 2020-02-05
  Description: In December 2019, Wuhan, in Hubei province, China, became the center of an outbreak of pneumonia of unknown cause. In a short time, Chinese scientists had shared the genome information of a novel coronavirus (2019-nCoV) from these pneumonia patients…
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  First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease.

  Tags Neonates, Pediatrics, R-Res&Pub, R-SP, R-T&C, Survivors, Therapeutics, Treatment and Care
  Creator: Dörnemann, Jenny, Chiara Burzio, Axelle Ronsse, Armand Sprecher, Hilde De Clerck, Michel Van Herp, Marie-Claire Kolié, Vesselina Yosifiva, Severine Caluwaerts, Anita K. McElroy, and Annick Antierens.
  Subject: Treatment & Care
  Item Type: Publication
  Date Last Updated: 2017-01-15
  Description: A neonate born to an Ebola virus-positive woman was diagnosed with Ebola virus infection on her first day of life.

• Corporate Report: Secure Specimen Transfer from Ebola Biobank to the UK (United Kingdom)

  Tags Ebola, R-Res&Pub, Specimen Transport, Therapeutics, Vaccine Study
  Creator: United Kingdom Department of Health (DH)
  Subject: Research
  Item Type: Guide
  Date Last Updated: 2019-07-19
  Description: This report summarizes the establishment of the Ebola Biobank, its governance, and how materials were safely transported in 2015 from West Africa to the United Kingdom for curation by Public Health England. The Biobank is a secure but accessible…