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Browse Items (107 total)
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Creator: PRINCIPLE Trial Collaborative Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-03-04
Description: Azithromycin, an antibiotic with potential antiviral and anti-inflammatory properties, has been used to treat COVID-19, but evidence from community randomised trials is lacking. We aimed to assess the effectiveness of azithromycin to treat suspected… -
Creator: The RECOVERY Collaborative Group.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. -
Creator: The REMAP-CAP Investigators
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. -
Creator: the PlasmAr Study Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-18
Description: Convalescent plasma is frequently administered to patients with Covid-19 and has been reported, largely on the basis of observational data, to improve clinical outcomes. Minimal data are available from adequately powered randomized, controlled… -
Creator: the Fundación INFANT–COVID-19 Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-18
Description: Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered earlier… -
Creator: The RECOVERY Collaborative Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-02
Description: Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatory actions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.A response to this article was… -
Creator: Huang, Edmund, and Stanley C. Jordan.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-10
Description: Nearly 10 months after the identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the virus responsible for coronavirus disease 2019 (Covid-19), therapeutic options remain limited. -
Creator: WHO Solidarity Trial Consortium
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-02
Description: World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a — in patients hospitalized with coronavirus disease 2019 (Covid-19). -
Creator: Cavalcanti, Alexandre B., Fernando G. Zampieri, Regis G. Rosa, Luciano C. P. Azevedo, Viviane C. Veiga, Alvaro Avezum, Lucas P. Damiani, Aline Marcadenti, Letícia Kawano-Dourado, Thiago Lisboa, Debora L. M. Junqueira, Pedro G. M. de Barros e Silva,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-11-19
Description: Hydroxychloroquine and azithromycin have been used to treat patients with coronavirus disease 2019 (Covid-19). However, evidence on the safety and efficacy of these therapies is limited. -
Creator: The RECOVERY Collaborative Group
Subject: Research
Item Type: Publication
Date Last Updated: 2020-11-19
Description: Hydroxychloroquine and chloroquine have been proposed as treatments for coronavirus disease 2019 (Covid-19) on the basis of in vitro activity and data from uncontrolled studies and small, randomized trials.