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Browse Items (289 total)
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Creator: Hegde, S. T., H. Salje, H. M. S. Sazzad, M. J. Hossain, M. Rahman, P. Daszak, J. D. Klena, S. T. Nichol, S. P. Luby, and E. S. Gurley.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2019-08-01
Description: Understanding the true burden of emergent diseases is critical for assessing public-health impact. However, surveillance often relies on hospital systems that only capture a minority of cases. We use the example of Nipah-virus infection in… -
Creator: Playford, E. G., T. Munro, S. M. Mahler, S. Elliott, M. Gerometta, K. L. Hoger, M. L. Jones, P. Griffin, K. D. Lynch, H. Carroll, D. El Saadi, M. E. Gilmour, B. Hughes, K. Hughes, E. Huang, C. de Bakker, R. Klein, M. G. Scher, I. L. Smith, L. F.…
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-04
Description: The monoclonal antibody m102.4 is a potent, fully human antibody that neutralises Hendra and Nipah viruses in vitro and in vivo. We aimed to investigate the safety, tolerability, pharmacokinetics, and immunogenicity of m102.4 in healthy adults. -
Creator: Michael K. Lo, Friederike Feldmann, Joy M. Gary, Robert Jordan, Roy Bannister, Jacqueline Cronin, Nishi R. Patel, John D. Klena, Stuart T. Nichol, Tomas Cihlar, Sherif R. Zaki, Heinz Feldmann, Christina F. Spiropoulou, and Emmie de Wit.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2019-05-29
Description: Nipah virus is an emerging pathogen in the Paramyxoviridae family. Upon transmission of Nipah virus from its natural reservoir, Pteropus spp. fruit bats, to humans, it causes respiratory and neurological disease with a case-fatality rate about 70%. -
Creator: The Medical Countermeasures Working Group of the National Emerging Special Pathogens Training and Education Center’s (NETEC’s) Special Pathogens Research Network (SPRN)
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2021-02-18
Description: This article is one of a series on acute, severe diseases of humans caused by emerging viruses for which there are no or limited licensed medical countermeasures. We approached this summary on South American Hemorrhagic Fevers (SAHF) from a clinical… -
Creator: Ya Gao, Yunli Zhao, Gordon Guyatt, Robert Fowler, Richard Kojan, Long Ge, Jinhui Tian, Collaborators; Qiukui Hao
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2022-07-05
Description: Specific treatments targeting Ebola virus are crucial in managing Ebola virus disease. To support the development of clinical practice guidelines on medications for Ebola virus disease, we aimed to evaluate the efficacy and safety of therapies for… -
Creator: Science Working Group of the National Emerging Special Pathogens Training and Education Center (NETEC) Special Pathogens Research Network (SPRN)
Subject: General
Item Type: Publication
Date Last Updated: 2022-04-05
Description: This summary on Lassa virus (LASV) infection and Lassa fever disease (LF) was developed from a clinical perspective to provide clinicians with a condensed, accessible understanding of the current literature. The information provided highlights… -
Creator: Abigail E Lowe, Colleen Kraft, Mark G Kortepeter, Keith F Hansen, Kristine Sanger, Ann Johnson, Jonathan D Grein, Julie Martin, Rebecca Rousselle, Jennifer A Garland, Jessica Spotts, John J Lowe, Lauren M Sauer, Christopher J Kratochvil, Bruce G…
Subject: Research
Item Type: Publication
Date Last Updated: 2022-05-31
Description: Research is foundational for evidence-based management of patients. Clinical research, however, takes time to plan, conduct, and disseminate—a luxury that is rarely available during a public health emergency. The University of Nebraska Medical Center… -
Creator: Kimon C Zachary, Erica S Shenoy
Subject: Infection Control
Item Type: Publication
Date Last Updated: 2022-06-09
Description: Transmission risk of monkeypox in healthcare settings outside endemic regions has not been well defined. A rapid review of the literature, including cases outside monkeypox-endemic regions from 2000 to 2022 identified a single reported case of… -
Creator: Theodore J Cieslak, Jocelyn J Herstein, Mark G Kortepeter, Angela L Hewlett
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2019-08-22
Description: Although the concept of high-level containment care (HLCC or ‘biocontainment’), dates back to 1969, the 2014–2016 outbreak of Ebola virus disease (EVD) brought with it a renewed emphasis on the use of specialized HLCC units in the care of patients… -
Creator: Vikramjit Mukherjee, Lauren M Sauer, Aneesh K Mehta, Sophia Y Shea, Paul D Biddinger, Brendan G Carr, Laura E Evans, Shelly Schwedhelm, John J Lowe, John J Lowe
Subject: Emergency Management
Item Type: Publication
Date Last Updated: 2022-05-31
Description: Infectious disease outbreaks and pandemics have repeatedly threatened public health and have severely strained healthcare delivery systems throughout the past century. Pathogens causing respiratory illness, such as influenza viruses and…
