South American Hemorrhagic Fevers: A summary for clinicians
Item
Click for External Resource*
Click to read full article*
*The link above may share a zip file (.zip) hosted on repository.netecweb.org. Zip files will download automatically.
*All other links are external and will open in a new window. If you click an external link, you are leaving the NETEC site, and we do not maintain, review, or endorse these materials. See our terms of use.
Files for Download
PIIS1201971221001326.pdfItem Type
PublicationTerms of Use
Document Viewer
Title
Subject
Description
Source
Date
Type
Citation
Abstract
Objectives: This article is one of a series on acute, severe diseases of humans caused by emerging viruses for which there are no or limited licensed medical countermeasures. We approached this summary on South American Hemorrhagic Fevers (SAHF) from a clinical perspective that focuses on pathogenesis, clinical features, and diagnostics with an emphasis on therapies and vaccines that have demonstrated potential for use in an emergency situation through their evaluation in nonhuman primates (NHPs) and/or in humans.
Methods: A standardized literature review was conducted on the clinical, pathological, vaccine, and treatment factors for SAHF as a group and for each individual virus/disease.
Results: We identified 2 treatments and 1 vaccine platform that have demonstrated potential benefit for treating or preventing infection in humans and 4 other potential treatments currently under investigation.
Conclusion: We provide succinct summaries of these countermeasures to give the busy clinician a head start in reviewing the literature if faced with a patient with South American Hemorrhagic Fever. We also provide links to other authoritative sources of information.
Keywords: Argentine hemorrhagic fever; Bolivian hemorrhagic fever; Brazilian hemorrhagic fever; Junín virus; Machupo virus; New World Arenavirus; South American hemorrhagic fevers; Venezuelan hemorrhagic fever.
Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Was this resource helpful?