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Navegar por los elementos (682 total)
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Autor: Bowring, Mary G., Zitong Wang, Yizhen Xu, Joshua Betz, John Muschelli, Brian T. Garibaldi, and Scott L. Zeger.
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2021-05-12
Descripción: Longitudinal trajectories of vital signs and biomarkers during admission remain poorly characterized for COVID-19 patients despite their potential to provide critical insights about disease progression. We studied 1884 patients with SARS-CoV2… -
Autor: Shaw, Robert H., Arabella Stuart, Melanie Greenland, Xinxue Liu, Jonathan S. Nguyen Van-Tam, and Matthew D. Snape.
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2021-05-12
Descripción: There is significant international interest in heterologous prime-boost COVID-19 vaccination to mitigate against supply shocks or shortages that might otherwise reduce the speed of vaccine roll-out. Additionally, in light of changing recommendations… -
Autor: Barksdale, Aaron Nathan, Wesley G. Zeger, Joshua L. Santarpia, Vicki L. Herrera, Daniel N. Ackerman, John J. Lowe, and Michael C. Wadman.
Tema: Physical Infrastructure
Tipo de elemento: Publicación
Fecha de actualización: 2021-04-31
Descripción: As a result of the COVID-19 pandemic and highly contagious nature of SARS-CoV-2, emergency departments (EDs) have been forced to implement new measures and protocols to minimize the spread of the disease within their departments. The primary… -
Autor: Leshem, Eyal, and Benjamin Alan Lopman.
Tema: Infection Control
Tipo de elemento: Publicación
Fecha de actualización: 2021-04-23
Descripción: Vaccines act by two broad main mechanisms. They can block infection occurring entirely or they can halt the progression to symptoms after infection occurs. -
Autor: Rosas, Ivan O., Norbert Bräu, Michael Waters, Ronaldo C. Go, Bradley D. Hunter, Sanjay Bhagani, Daniel Skiest, Mariam S. Aziz, Nichola Cooper, Ivor S. Douglas, Sinisa Savic, Taryn Youngstein, Lorenzo Del Sorbo, Antonio Cubillo Gracian, David J. De La…
Tema: Treatment & Care
Tipo de elemento: Publicación
Fecha de actualización: 2021-04-22
Descripción: Coronavirus disease 2019 (Covid-19) is associated with immune dysregulation and hyperinflammation, including elevated interleukin-6 levels. The use of tocilizumab, a monoclonal antibody against the interleukin-6 receptor, has resulted in better… -
Autor: Hacisuleyman, Ezgi, Caryn Hale, Yuhki Saito, Nathalie E. Blachere, Marissa Bergh, Erin G. Conlon, Dennis J. Schaefer-Babajew, Justin DaSilva, Frauke Muecksch, Christian Gaebler, Richard Lifton, Michel C. Nussenzweig, Theodora Hatziioannou, Paul D.…
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2021-04-21
Descripción: Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 (Pfizer–BioNTech) or mRNA-1273 (Moderna) vaccine at least 2 weeks… -
Autor: Chappell, Keith J., Francesca L. Mordant, Zheyi Li, Danushka K. Wijesundara, Paula Ellenberg, Julia A. Lackenby, Stacey T. M. Cheung, Naphak Modhiran, Michael S. Avumegah, Christina L. Henderson, Kym Hoger, Paul Griffin, Jillian Bennet, Luca Hensen,…
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2021-04-19
Descripción: Given the scale of the ongoing COVID-19 pandemic, the development of vaccines based on different platforms is essential, particularly in light of emerging viral variants, the absence of information on vaccine-induced immune durability, and potential… -
Autor: Goepfert, Paul A., Bo Fu, Anne-Laure Chabanon, Matthew I. Bonaparte, Matthew G. Davis, Brandon J. Essink, Ian Frank, Owen Haney, Helene Janosczyk, Michael C. Keefer, Marguerite Koutsoukos, Murray A. Kimmel, Roger Masotti, Stephen J. Savarino, Lode…
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2021-04-19
Descripción: CoV2 preS dTM is a stabilised pre-fusion spike protein vaccine produced in a baculovirus expression system being developed against SARS-CoV-2. We present interim safety and immunogenicity results of the first-in-human study of the CoV2 preS dTM… -
Autor: Hunt, Richard C., Bruce B. Struminger, John T. Redd, Jack Herrmann, B. Tilman Jolly, Sanjeev Arora, Amy J. Armistad, Amanda M. Dezan, Celine A. Bennett, Jon R. Krohmer, and Lawrence H. Brown.
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2021-04-17
Descripción: Tasked with identifying digital health solutions to support dynamic learning health systems and their response to COVID-19, the U.S. Department of Health and Human Services Office of the Assistant Secretary for Preparedness and Response partnered… -
Autor: Antar, Annukka A. R., Tong Yu, Nora Pisanic, Razvan Azamfirei, Jeffrey A. Tornheim, Diane M. Brown, Kate Kruczynski, Justin P. Hardick, Thelio Sewell, Minyoung Jang, Taylor Church, Samantha N. Walch, Carolyn Reuland, Vismaya S. Bachu, Kirsten…
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2021-04-16
Descripción: Sustained molecular detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in the upper respiratory tract (URT) in mild to moderate coronavirus disease 2019 (COVID-19) is common. We sought to identify host and immune…