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Prevention of the cytokine storm in COVID-19


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Prevention of the cytokine storm in COVID-19



The Comment by Marc Feldman and colleagues,1 published recently in The Lancet, discussed the potential of anti-tumor necrosis factor (TNF) therapy to inhibit development of a cytokine storm in patients with coronavirus disease 2019 (COVID-19). Following this Comment, I write to propose that the opioid, meptazinol, might be a possible alternative or addition to anti-TNF therapy, particularly in the UK, where meptazinol is a licensed drug (current licenced supplier Almirall, Barcelona, Spain) and thus could be easily prescribed.




Wright, David J. M. 2020. "Prevention of the cytokine storm in COVID-19." The Lancet Infectious Diseases.


Free online on Lancet site.