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Browse Items (308 total)
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Creator: Jocelyn J Herstein, Paul D Biddinger, Shawn G Gibbs, Angela L Hewlett, Aurora B Le, Michelle M Schwedhelm, John J Lowe
Subject: Research
Item Type: Publication
Date Last Updated: 2022-02-22
Description: In response to the 2014-2016 West Africa Ebola virus disease (EVD) epidemic, the Centers for Disease Control and Prevention (CDC) designated 56 US hospitals as Ebola treatment centers (ETCs) with high-level isolation capabilities. We aimed to… -
Creator: Shantha, J. G., I. Crozier, C. S. Kraft, D. G. Grant, A. Goba, B. R. Hayek, C. Hartley, K. G. Barnes, T. M. Uyeki, J. Schieffelin, R. F. Garry, D. G. Bausch, P. E. Farmer, J. G. Mattia, M. J. Vandy, and S. Yeh.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-07-09
Description: Following the West African Ebola virus disease (EVD) outbreak of 2013-2016 and more recent EVD outbreaks in the Democratic Republic of Congo, thousands of EVD survivors are at-risk for sequelae including uveitis, which can lead to unremitting… -
Creator: Schafer, Adam, Rui Xiong, Laura Cooper, Raghad Nowar, Hyun Lee, Yangfeng Li, Benjamin E. Ramirez, Norton P. Peet, Michael Caffrey, Gregory R. J. Thatcher, Erica Ollmann Saphire, Han Cheng, and Lijun Rong.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-04
Description: Many small molecules have been identified as entry inhibitors of filoviruses. However, a lack of understanding of the mechanism of action for these molecules limits further their development as anti-filoviral agents. Here we provide evidence that… -
Creator: Mbala-Kingebeni, Placide, Catherine Pratt, Mbusa Mutafali-Ruffin, Matthias G. Pauthner, Faustin Bile, Antoine Nkuba-Ndaye, Allison Black, Eddy Kinganda-Lusamaki, Martin Faye, Amuri Aziza, Moussa M. Diagne, Daniel Mukadi, Bailey White, James Hadfield,…
Subject: Research
Item Type: Publication
Description: During the 2018–2020 Ebola virus disease (EVD) outbreak in North Kivu province in the Democratic Republic of Congo, EVD was diagnosed in a patient who had received the recombinant vesicular stomatitis virus–based vaccine expressing a ZEBOV… -
Creator: Blair, P. W., M. G. Kortepeter, L. G. Downey, C. S. Madar, I. L. Downs, K. A. Martins, F. Rossi, J. A. Williams, A. Madar, C. W. Schellhase, J. J. Bearss, X. Zeng, S. Bavari, V. Soloveva, J. B. Wells, K. S. Stuthman, N. L. Garza, S. A. Vantongeren,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-25
Description: Ebola virus disease (EVD) supportive care strategies are largely guided by retrospective observational research. This study investigated the effect of EVD supportive care algorithms on duration of survival in a controlled nonhuman primate (NHP)… -
Creator: Thom, Ruth, Thomas Tipton, Thomas Strecker, Yper Hall, Joseph Akoi Bore, Piet Maes, Fara Raymond Koundouno, Sarah Katharina Fehling, Verena Krähling, Kimberley Steeds, Anitha Varghese, Graham Bailey, Mary Matheson, Moussa Coné, Balla Moussa Keita,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-13
Description: The 2013–16 Ebola virus disease epidemic in west Africa caused international alarm due to its rapid and extensive spread resulting in a significant death toll and social unrest within the affected region. The large number of cases provided an… -
Creator: Iversen, Patrick L., Christopher D. Kane, Xiankun Zeng, Rekha G. Panchal, Travis K. Warren, Sheli R. Radoshitzky, Jens H. Kuhn, Rajini R. Mudhasani, Christopher L. Cooper, Amy C. Shurtleff, Farooq Nasar, Melek M. E. Sunay, Allen J. Duplantier, Brett…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-06-18
Description: The PALM trial in the Democratic Republic of the Congo identified a statistically significant survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute Ebola virus disease; however, substantial gaps remain in improving… -
Creator: McElroy, Anita K., Rama S. Akondy, David R. McLlwain, Han Chen, Zach Bjornson-Hooper, Nilanjan Mukherjee, Aneesh K. Mehta, Garry Nolan, Stuart T. Nichol, and Christina F. Spiropoulou.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-05-21
Description: A complete understanding of human immune responses to Ebola virus infection is limited by the availability of specimens and the requirement for biosafety level 4 (BSL-4) containment. -
Creator: Tapia, Milagritos D., Samba O. Sow, Khardiata D. Mbaye, Aliou Thiongane, Birahim P. Ndiaye, Cheikh T. Ndour, Souleymane Mboup, Babajide Keshinro, Thompson N. Kinge, Guy Vernet, Jean Joel Bigna, Stephen Oguche, Kwadwo A. Koram, Kwaku P. Asante,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-03-19
Description: During the large 2013–16 Ebola virus outbreak caused by the Zaire Ebola virus, about 20% of cases were reported in children. This study is the first, to our knowledge, to evaluate an Ebola vaccine in children younger than 6 years. -
Creator: Tapia, Milagritos D., Samba O. Sow, Birahim P. Ndiaye, Khardiata D. Mbaye, Aliou Thiongane, Cheikh T. Ndour, Souleymane Mboup, Julie A. Ake, Babajide Keshinro, Gideon A. Akintunde, Thompson N. Kinge, Guy Vernet, Jean Joel Bigna, Stephen Oguche,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-03-19
Description: The 2014 Zaire Ebola virus disease epidemic accelerated vaccine development for the virus.