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Browse Items (100 total)
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Creator: Horby, Peter W., Marion Mafham, Jennifer L. Bell, Louise Linsell, Natalie Staplin, Jonathan Emberson, Adrian Palfreeman, Jason Raw, Einas Elmahi, Benjamin Prudon, Christopher Green, Simon Carley, David Chadwick, Matthew Davies, Matthew P. Wise, J.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-05
Description: Lopinavir–ritonavir has been proposed as a treatment for COVID-19 on the basis of in vitro activity, preclinical studies, and observational studies. Here, we report the results of a randomised trial to assess whether lopinavir–ritonavir improves… -
Creator: Anand, Shuchi, Maria Montez-Rath, Jialin Han, Julie Bozeman, Russell Kerschmann, Paul Beyer, Julie Parsonnet, and Glenn M. Chertow.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-25
Description: Many patients receiving dialysis in the USA share the socioeconomic characteristics of underserved communities, and undergo routine monthly laboratory testing, facilitating a practical, unbiased, and repeatable assessment of severe acute respiratory… -
Creator: Wyllie, Anne L., John Fournier, Arnau Casanovas-Massana, Melissa Campbell, Maria Tokuyama, Pavithra Vijayakumar, Joshua L. Warren, Bertie Geng, M. Catherine Muenker, Adam J. Moore, Chantal B. F. Vogels, Mary E. Petrone, Isabel M. Ott, Peiwen Lu,…
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-09-24
Description: Rapid and accurate diagnostic tests are essential for controlling the ongoing Covid-19 pandemic. Although the current standard involves testing of nasopharyngeal swab specimens by quantitative reverse-transcriptase polymerase chain reaction (RT-qPCR)… -
Creator: McClain, Micah T., Florica J. Constantine, Bradly P. Nicholson, Marshall Nichols, Thomas W. Burke, Ricardo Henao, Daphne C. Jones, Lori L. Hudson, L. Brett Jaggers, Timothy Veldman, Anna Mazur, Lawrence P. Park, Sunil Suchindran, Ephraim L. Tsalik,…
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-09-24
Description: Early and accurate identification of individuals with viral infections is crucial for clinical management and public health interventions. We aimed to assess the ability of transcriptomic biomarkers to identify naturally acquired respiratory viral… -
Creator: The National SARS-CoV-2 Serology Assay Evaluation Group
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-09-23
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic in 2020. Testing is crucial for mitigating public health and economic effects. Serology is considered key to population-level surveillance and potentially… -
Creator: Dugdale, C. M., S. E. Turbett, S. M. McCluskey, K. C. Zachary, E. S. Shenoy, A. L. Ciaranello, R. P. Walensky, E. S. Rosenberg, M. N. Anahtar, D. C. Hooper, and E. P. Hyle.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-24
Description: We describe an approach to the evaluation and isolation of hospitalized persons under investigation (PUIs) for COVID-19 at a large U.S. academic medical center. Only a small proportion (2.9%) of PUIs with one or more repeat SARS-CoV-2 nucleic acid… -
Creator: Grassly, Nicholas C., Margarita Pons-Salort, Edward P. K. Parker, Peter J. White, Neil M. Ferguson, Kylie Ainslie, Marc Baguelin, Samir Bhatt, Adhiratha Boonyasiri, Nick Brazeau, Lorenzo Cattarino, Helen Coupland, Zulma Cucunuba, Gina…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: WHO has called for increased testing in response to the COVID-19 pandemic, but countries have taken different approaches and the effectiveness of alternative strategies is unknown. We aimed to investigate the potential impact of different testing and… -
Creator: Jamiolkowski, Dagmar, Beda Mühleisen, Simon Müller, Alexander A. Navarini, Alexandar Tzankov, and Elisabeth Roider.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-08-13
Description: Understanding the disease course and prevalence of COVID-19 is important not only for medical, but also for socioeconomic reasons. So far, COVID-19 has been understood as a multisystem disease, mainly affecting the lungs, kidneys, and heart. -
Creator: Arora, Rahul K., Abel Joseph, Jordan Van Wyk, Simona Rocco, Austin Atmaja, Ewan May, Tingting Yan, Niklas Bobrovitz, Jonathan Chevrier, Matthew P. Cheng, Tyler Williamson, and David L. Buckeridge.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-04
Description: As the initial phase of the COVID-19 pandemic passes its peak in many countries, serological studies are becoming increasingly important in guiding public health responses. Antibody testing is crucial for monitoring the evolution of the pandemic,… -
Creator: Ibarrondo, F. Javier, Jennifer A. Fulcher, David Goodman-Meza, Julie Elliott, Christian Hofmann, Mary A. Hausner, Kathie G. Ferbas, Nicole H. Tobin, Grace M. Aldrovandi, and Otto O. Yang.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-07-21
Description: A recent article suggested the rapid decay of anti–SARS-CoV-2 IgG in early infection, but the rate was not described in detail. We evaluated persons who had recovered from Covid-19 and referred themselves to our institution for observational…