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Browse Items (852 total)
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Creator: Horby, Peter W., Marion Mafham, Jennifer L. Bell, Louise Linsell, Natalie Staplin, Jonathan Emberson, Adrian Palfreeman, Jason Raw, Einas Elmahi, Benjamin Prudon, Christopher Green, Simon Carley, David Chadwick, Matthew Davies, Matthew P. Wise, J.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-05
Description: Lopinavir–ritonavir has been proposed as a treatment for COVID-19 on the basis of in vitro activity, preclinical studies, and observational studies. Here, we report the results of a randomised trial to assess whether lopinavir–ritonavir improves… -
Creator: Mok, Chris Ka Pun, Airu Zhu, Jingxian Zhao, Eric H. Y. Lau, Junxiang Wang, Zhao Chen, Zhen Zhuang, Yanqun Wang, Abeer N. Alshukairi, Salim A. Baharoon, Wenling Wang, Wenjie Tan, Weiwen Liang, Jamiu O. Oladipo, Ranawaka A. P. M. Perera, Sulyman A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-06
Description: Middle East respiratory syndrome (MERS) remains of global public health concern. Dromedary camels are the source of zoonotic infection. Over 70% of MERS coronavirus (MERS-CoV)-infected dromedaries are found in Africa but no zoonotic disease has been… -
Creator: Arabi, Yaseen M., Ayed Y. Asiri, Abdullah M. Assiri, Hanan H. Balkhy, Ali Al Bshabshe, Majed Al Jeraisy, Yasser Mandourah, Mohamed H. A. Azzam, Abdulhadi M. Bin Eshaq, Sameera Al Johani, Shmeylan Al Harbi, Hani A. A. Jokhdar, Ahmad M. Deeb, Ziad A.…
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-10-07
Description: Whether combined treatment with recombinant interferon beta-1b and lopinavir–ritonavir reduces mortality among patients hospitalized with Middle East respiratory syndrome (MERS) is unclear. -
Creator: Tillett, Richard L., Joel R. Sevinsky, Paul D. Hartley, Heather Kerwin, Natalie Crawford, Andrew Gorzalski, Chris Laverdure, Subhash C. Verma, Cyprian C. Rossetto, David Jackson, Megan J. Farrell, Stephanie Van Hooser, and Mark Pandori.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-12
Description: The degree of protective immunity conferred by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the possibility of reinfection with SARS-CoV-2 is not well understood. We describe an… -
Creator: Iwasaki, Akiko.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-12
Description: One of the key questions in predicting the course of the COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is how well and how long the immune responses protect the host from reinfection.A response to this… -
Creator: Thom, Ruth, Thomas Tipton, Thomas Strecker, Yper Hall, Joseph Akoi Bore, Piet Maes, Fara Raymond Koundouno, Sarah Katharina Fehling, Verena Krähling, Kimberley Steeds, Anitha Varghese, Graham Bailey, Mary Matheson, Moussa Coné, Balla Moussa Keita,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-13
Description: The 2013–16 Ebola virus disease epidemic in west Africa caused international alarm due to its rapid and extensive spread resulting in a significant death toll and social unrest within the affected region. The large number of cases provided an… -
Creator: Poland, Gregory A., Inna G. Ovsyannikova, and Richard B. Kennedy.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-10-13
Description: Understanding immune responses to severe acute respiratory syndrome coronavirus 2 is crucial to understanding disease pathogenesis and the usefulness of bridge therapies, such as hyperimmune globulin and convalescent human plasma, and to developing… -
Creator: Ward, Brian J., Alexander Makarkov, Annie Séguin, Stéphane Pillet, Sonia Trépanier, Jiwanjeet Dhaliwall, Michael D. Libman, Timo Vesikari, and Nathalie Landry.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-10-13
Description: Seasonal influenza remains a substantial public health threat despite the availability of egg-derived and other vaccines. Plant-based manufacturing might address some of the limitations of current vaccines. We describe two phase 3 efficacy studies of… -
Creator: Xia, Shengli, Yuntao Zhang, Yanxia Wang, Hui Wang, Yunkai Yang, George Fu Gao, Wenjie Tan, Guizhen Wu, Miao Xu, Zhiyong Lou, Weijin Huang, Wenbo Xu, Baoying Huang, Huijuan Wang, Wei Wang, Wei Zhang, Na Li, Zhiqiang Xie, Ling Ding, Wangyang You, Yuxiu…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-15
Description: The ongoing COVID-19 pandemic warrants accelerated efforts to test vaccine candidates. We aimed to assess the safety and immunogenicity of an inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidate, BBIBP-CorV, in… -
Creator: Walsh, Edward E., Robert W. Frenck, Ann R. Falsey, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen Lockhart, Kathleen Neuzil, Mark J. Mulligan, Ruth Bailey, Kena A. Swanson, Ping Li, Kenneth Koury, Warren Kalina, David Cooper, Camila…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-14
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and the resulting disease, coronavirus disease 2019 (Covid-19), have spread to millions of persons worldwide. Multiple vaccine candidates are under development, but no vaccine is…