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Browse Items (325 total)
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Creator: Thompson, Elizabeth A., Katherine Cascino, Alvaro A. Ordonez, Weiqiang Zhou, Ajay Vaghasia, Anne Hamacher-Brady, Nathan R. Brady, Im-Hong Sun, Rulin Wang, Avi Z. Rosenberg, Michael Delannoy, Richard Rothman, Katherine Fenstermacher, Lauren Sauer,…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-26
Description: It is unclear why some SARS-CoV-2 patients readily resolve infection while others develop severe disease. By interrogating metabolic programs of immune cells in severe and recovered coronavirus disease 2019 (COVID-19) patients compared with other… -
Creator: Manisty, Charlotte, Ashley D. Otter, Thomas A. Treibel, Áine McKnight, Daniel M. Altmann, Timothy Brooks, Mahdad Noursadeghi, Rosemary J. Boyton, Amanda Semper, and James C. Moon.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: Rapid vaccine-induced population immunity is a key global strategy to control COVID-19. Vaccination programmes must maximise early impact, particularly with accelerated spread of new variants. -
Creator: Prendecki, Maria, Candice Clarke, Jonathan Brown, Alison Cox, Sarah Gleeson, Mary Guckian, Paul Randell, Alessia Dalla Pria, Liz Lightstone, Xiao-Ning Xu, Wendy Barclay, Stephen P. McAdoo, Peter Kelleher, and Michelle Willicombe.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: The rapid implementation of SARS-CoV-2 vaccination is now a global health-care priority. Successful phase 3 trial outcomes have been reported for numerous vaccines that induce robust humoral and cellular immune responses against the SARS-CoV-2 spike… -
Creator: The RECOVERY Collaborative Group.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. -
Creator: The REMAP-CAP Investigators
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. -
Creator: Dagan, Noa, Noam Barda, Eldad Kepten, Oren Miron, Shay Perchik, Mark A. Katz, Miguel A. Hernán, Marc Lipsitch, Ben Reis, and Ran D. Balicer.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-24
Description: As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse populations in a noncontrolled setting. In this study, data from Israel’s… -
Creator: the Oxford COVID Vaccine Trial Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-19
Description: The ChAdOx1 nCoV-19 (AZD1222) vaccine has been approved for emergency use by the UK regulatory authority, Medicines and Healthcare products Regulatory Agency, with a regimen of two standard doses given with an interval of 4–12 weeks. -
Creator: the PlasmAr Study Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-18
Description: Convalescent plasma is frequently administered to patients with Covid-19 and has been reported, largely on the basis of observational data, to improve clinical outcomes. Minimal data are available from adequately powered randomized, controlled… -
Creator: the Fundación INFANT–COVID-19 Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-18
Description: Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered earlier… -
Creator: Wu, Kai, Anne P. Werner, Matthew Koch, Angela Choi, Elisabeth Narayanan, Guillaume B. E. Stewart-Jones, Tonya Colpitts, Hamilton Bennett, Seyhan Boyoglu-Barnum, Wei Shi, Juan I. Moliva, Nancy J. Sullivan, Barney S. Graham, Andrea Carfi, Kizzmekia S.…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-17
Description: The mRNA-1273 vaccine against SARS-CoV-2 elicited high neutralizing-antibody titers in phase 1 trial participants and has been shown to be highly efficacious in preventing symptomatic Covid-19 disease and severe disease.