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Parcourir les contenus (73 total)
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Créateur: Brett-Major, David M., Elizabeth R. Schnaubelt, Hannah M. Creager, Abigail Lowe, Theodore J. Cieslak, Jacob M. Dahlke, Daniel W. Johnson, Paul D. Fey, Keith F. Hansen, Angela L. Hewlett, Bruce G. Gordon, Andre C. Kalil, Ali S. Khan, Mark G.…
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2020-03-30
Description: The optimal time to initiate research on emergencies is before they occur. However, timely initiation of high-quality research may launch during an emergency under the right conditions. -
Créateur: Yi, Eunhee S., Matthew J. Cecchini, and Melanie C. Bois.
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2020-06-08
Description: The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in more than 5·7 million confirmed cases and 350 000 deaths globally as of May 28, according to the Johns Hopkins University Coronavirus… -
Créateur: Marshall, John C., Srinivas Murthy, Janet Diaz, Neil Adhikari, Derek C. Angus, Yaseen M. Arabi, Kenneth Baillie, Michael Bauer, Scott Berry, Bronagh Blackwood, Marc Bonten, Fernando Bozza, Frank Brunkhorst, Allen Cheng, Mike Clarke, Vu Quoc Dat,…
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2020-06-12
Description: Clinical research is necessary for an effective response to an emerging infectious disease outbreak. However, research efforts are often hastily organised and done using various research tools, with the result that pooling data across studies is… -
Créateur: Dugdale, C. M., S. E. Turbett, S. M. McCluskey, K. C. Zachary, E. S. Shenoy, A. L. Ciaranello, R. P. Walensky, E. S. Rosenberg, M. N. Anahtar, D. C. Hooper, and E. P. Hyle.
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2020-08-24
Description: We describe an approach to the evaluation and isolation of hospitalized persons under investigation (PUIs) for COVID-19 at a large U.S. academic medical center. Only a small proportion (2.9%) of PUIs with one or more repeat SARS-CoV-2 nucleic acid… -
Créateur: Suthar, M. S., M. G. Zimmerman, R. C. Kauffman, G. Mantus, S. L. Linderman, W. H. Hudson, A. Vanderheiden, L. Nyhoff, C. W. Davis, O. Adekunle, M. Affer, M. Sherman, S. Reynolds, H. P. Verkerke, D. N. Alter, J. Guarner, J. Bryksin, M. C. Horwath, C.…
Sujet: Laboratory
Type d'élément: Publication
Date de la dernière mise à jour: 2020-06-23
Description: SARS-CoV-2, the virus responsible for COVID-19, is causing a devastating worldwide pandemic, and there is a pressing need to understand the development, specificity, and neutralizing potency of humoral immune responses during acute infection. We… -
Créateur: Sakurai, Aki, Toshiharu Sasaki, Shigeo Kato, Masamichi Hayashi, Sei-ichiro Tsuzuki, Takuma Ishihara, Mitsunaga Iwata, Zenichi Morise, and Yohei Doi.
Sujet: Infection Control
Type d'élément: Publication
Date de la dernière mise à jour: 2020-08-27
Description: Information on the natural history of asymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains scarce. -
Créateur: Davis, Carl W., Katherine J. L. Jackson, Megan M. McCausland, Jaime Darce, Cathy Chang, Susanne L. Linderman, Chakravarthy Chennareddy, Rebecca Gerkin, Shantoria J. Brown, Jens Wrammert, Aneesh K. Mehta, Wan Cheung Cheung, Scott D. Boyd, Edmund K.…
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2020-08-13
Description: A universal vaccine against influenza would ideally generate protective immune responses that are not only broadly reactive against multiple influenza strains, but also long-lasting. Because long-term serum antibody levels are maintained by bone… -
Créateur: Mengfei Chen, Wenjuan Shen, Nicholas R. Rowan, Heather Kulaga, Alexander Hillel, Murugappan Ramanathan Jr, and Andrew P. Lane.
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2020-08-18
Description: ACE2 protein is expressed at high levels in the human olfactory epithelium relative to upper airway epithelial cells. This may explain COVID-19-associated olfactory dysfunction, while suggesting a SARS-CoV-2 reservoir site and potential intranasal… -
Créateur: Young, Barnaby E., Siew-Wai Fong, Yi-Hao Chan, Tze-Minn Mak, Li Wei Ang, Danielle E. Anderson, Cheryl Yi-Pin Lee, Siti Naqiah Amrun, Bernett Lee, Yun Shan Goh, Yvonne C. F. Su, Wycliffe E. Wei, Shirin Kalimuddin, Louis Yi Ann Chai, Surinder Pada,…
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2020-08-18
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with a 382-nucleotide deletion (∆382) in the open reading frame 8 (ORF8) region of the genome have been detected in Singapore and other countries. We investigated the effect of… -
Créateur: Grassly, Nicholas C., Margarita Pons-Salort, Edward P. K. Parker, Peter J. White, Neil M. Ferguson, Kylie Ainslie, Marc Baguelin, Samir Bhatt, Adhiratha Boonyasiri, Nick Brazeau, Lorenzo Cattarino, Helen Coupland, Zulma Cucunuba, Gina…
Sujet: Research
Type d'élément: Publication
Date de la dernière mise à jour: 2020-08-18
Description: WHO has called for increased testing in response to the COVID-19 pandemic, but countries have taken different approaches and the effectiveness of alternative strategies is unknown. We aimed to investigate the potential impact of different testing and…