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Browse Items (73 total)
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Creator: Suthar, Mehul S., Matthew G. Zimmerman, Robert C. Kauffman, Grace Mantus, Susanne L. Linderman, William H. Hudson, Abigail Vanderheiden, Lindsay Nyhoff, Carl W. Davis, Oluwaseyi Adekunle, Maurizio Affer, Melanie Sherman, Stacian Reynolds, Hans P.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-06-23
Description: SARS-CoV-2, the virus responsible for COVID-19, is causing a devastating worldwide pandemic, and there is a pressing need to understand the development, specificity, and neutralizing potency of humoral immune responses during acute infection. -
Creator: Grassly, Nicholas C., Margarita Pons-Salort, Edward P. K. Parker, Peter J. White, Neil M. Ferguson, Kylie Ainslie, Marc Baguelin, Samir Bhatt, Adhiratha Boonyasiri, Nick Brazeau, Lorenzo Cattarino, Helen Coupland, Zulma Cucunuba, Gina…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: WHO has called for increased testing in response to the COVID-19 pandemic, but countries have taken different approaches and the effectiveness of alternative strategies is unknown. We aimed to investigate the potential impact of different testing and… -
Creator: Young, Barnaby E., Siew-Wai Fong, Yi-Hao Chan, Tze-Minn Mak, Li Wei Ang, Danielle E. Anderson, Cheryl Yi-Pin Lee, Siti Naqiah Amrun, Bernett Lee, Yun Shan Goh, Yvonne C. F. Su, Wycliffe E. Wei, Shirin Kalimuddin, Louis Yi Ann Chai, Surinder Pada,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with a 382-nucleotide deletion (∆382) in the open reading frame 8 (ORF8) region of the genome have been detected in Singapore and other countries. We investigated the effect of… -
Creator: Mengfei Chen, Wenjuan Shen, Nicholas R. Rowan, Heather Kulaga, Alexander Hillel, Murugappan Ramanathan Jr, and Andrew P. Lane.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: ACE2 protein is expressed at high levels in the human olfactory epithelium relative to upper airway epithelial cells. This may explain COVID-19-associated olfactory dysfunction, while suggesting a SARS-CoV-2 reservoir site and potential intranasal… -
Creator: Davis, Carl W., Katherine J. L. Jackson, Megan M. McCausland, Jaime Darce, Cathy Chang, Susanne L. Linderman, Chakravarthy Chennareddy, Rebecca Gerkin, Shantoria J. Brown, Jens Wrammert, Aneesh K. Mehta, Wan Cheung Cheung, Scott D. Boyd, Edmund K.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-13
Description: A universal vaccine against influenza would ideally generate protective immune responses that are not only broadly reactive against multiple influenza strains, but also long-lasting. Because long-term serum antibody levels are maintained by bone… -
Creator: Sakurai, Aki, Toshiharu Sasaki, Shigeo Kato, Masamichi Hayashi, Sei-ichiro Tsuzuki, Takuma Ishihara, Mitsunaga Iwata, Zenichi Morise, and Yohei Doi.
Subject: Infection Control
Item Type: Publication
Date Last Updated: 2020-08-27
Description: Information on the natural history of asymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains scarce. -
Creator: Suthar, M. S., M. G. Zimmerman, R. C. Kauffman, G. Mantus, S. L. Linderman, W. H. Hudson, A. Vanderheiden, L. Nyhoff, C. W. Davis, O. Adekunle, M. Affer, M. Sherman, S. Reynolds, H. P. Verkerke, D. N. Alter, J. Guarner, J. Bryksin, M. C. Horwath, C.…
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-06-23
Description: SARS-CoV-2, the virus responsible for COVID-19, is causing a devastating worldwide pandemic, and there is a pressing need to understand the development, specificity, and neutralizing potency of humoral immune responses during acute infection. We… -
Creator: Dugdale, C. M., S. E. Turbett, S. M. McCluskey, K. C. Zachary, E. S. Shenoy, A. L. Ciaranello, R. P. Walensky, E. S. Rosenberg, M. N. Anahtar, D. C. Hooper, and E. P. Hyle.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-24
Description: We describe an approach to the evaluation and isolation of hospitalized persons under investigation (PUIs) for COVID-19 at a large U.S. academic medical center. Only a small proportion (2.9%) of PUIs with one or more repeat SARS-CoV-2 nucleic acid… -
Creator: Logunov, Denis Y., Inna V. Dolzhikova, Olga V. Zubkova, Amir I. Tukhvatullin, Dmitry V. Shcheblyakov, Alina S. Dzharullaeva, Daria M. Grousova, Alina S. Erokhova, Anna V. Kovyrshina, Andrei G. Botikov, Fatima M. Izhaeva, Olga Popova, Tatiana A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-21
Description: We developed a heterologous COVID-19 vaccine consisting of two components, a recombinant adenovirus type 26 (rAd26) vector and a recombinant adenovirus type 5 (rAd5) vector, both carrying the gene for severe acute respiratory syndrome coronavirus 2… -
Creator: Solomon, Isaac H., Erica Normandin, Shamik Bhattacharyya, Shibani S. Mukerji, Kiana Keller, Ahya S. Ali, Gordon Adams, Jason L. Hornick, Robert F. Padera, and Pardis Sabeti.
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2020-09-03
Description: Neurologic symptoms, including headache, altered mental status, and anosmia, occur in many patients with Covid-19.