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Browse Items (1478 total)
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Creator: NIH
Subject: Infection Control
Item Type: Hyperlink
Date Last Updated: 2020-05-04
Description: This is a phase I, open-label, dose ranging clinical trial in males and non-pregnant females, starting at 18 years of age, inclusive, who are in good health and meet all eligibility criteria. This clinical trial is designed to assess the safety,… -
Creator: Walsh, Edward E., Robert W. Frenck, Ann R. Falsey, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen Lockhart, Kathleen Neuzil, Mark J. Mulligan, Ruth Bailey, Kena A. Swanson, Ping Li, Kenneth Koury, Warren Kalina, David Cooper, Camila…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-14
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and the resulting disease, coronavirus disease 2019 (Covid-19), have spread to millions of persons worldwide. Multiple vaccine candidates are under development, but no vaccine is… -
Creator: Oxford COVID Vaccine Trial Group
Subject: Research
Item Type: Publication
Date Last Updated: 2020-07-20
Description: The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might be curtailed by vaccination. We assessed the safety, reactogenicity, and immunogenicity of a viral vectored coronavirus vaccine that expresses the spike protein of… -
Creator: Goepfert, Paul A., Bo Fu, Anne-Laure Chabanon, Matthew I. Bonaparte, Matthew G. Davis, Brandon J. Essink, Ian Frank, Owen Haney, Helene Janosczyk, Michael C. Keefer, Marguerite Koutsoukos, Murray A. Kimmel, Roger Masotti, Stephen J. Savarino, Lode…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-04-19
Description: CoV2 preS dTM is a stabilised pre-fusion spike protein vaccine produced in a baculovirus expression system being developed against SARS-CoV-2. We present interim safety and immunogenicity results of the first-in-human study of the CoV2 preS dTM… -
Creator: Anderson, Evan J., Nadine G. Rouphael, Alicia T. Widge, Lisa A. Jackson, Paul C. Roberts, Mamodikoe Makhene, James D. Chappell, Mark R. Denison, Laura J. Stevens, Andrea J. Pruijssers, Adrian B. McDermott, Britta Flach, Bob C. Lin, Nicole A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-17
Description: Testing of vaccine candidates to prevent infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an older population is important, since increased incidences of illness and death from coronavirus disease 2019 (Covid-19) have… -
Creator: Richmond, Peter, Lara Hatchuel, Min Dong, Brenda Ma, Branda Hu, Igor Smolenov, Ping Li, Peng Liang, Htay Htay Han, Joshua Liang, and Ralf Clemens.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-01-29
Description: As part of the accelerated development of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we report a dose-finding and adjuvant justification study of SCB-2019, a protein subunit vaccine candidate containing a… -
Creator: Logunov, Denis Y., Inna V. Dolzhikova, Olga V. Zubkova, Amir I. Tukhvatullin, Dmitry V. Shcheblyakov, Alina S. Dzharullaeva, Daria M. Grousova, Alina S. Erokhova, Anna V. Kovyrshina, Andrei G. Botikov, Fatima M. Izhaeva, Olga Popova, Tatiana A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-21
Description: We developed a heterologous COVID-19 vaccine consisting of two components, a recombinant adenovirus type 26 (rAd26) vector and a recombinant adenovirus type 5 (rAd5) vector, both carrying the gene for severe acute respiratory syndrome coronavirus 2… -
Creator: Chappell, Keith J., Francesca L. Mordant, Zheyi Li, Danushka K. Wijesundara, Paula Ellenberg, Julia A. Lackenby, Stacey T. M. Cheung, Naphak Modhiran, Michael S. Avumegah, Christina L. Henderson, Kym Hoger, Paul Griffin, Jillian Bennet, Luca Hensen,…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-04-19
Description: Given the scale of the ongoing COVID-19 pandemic, the development of vaccines based on different platforms is essential, particularly in light of emerging viral variants, the absence of information on vaccine-induced immune durability, and potential… -
Creator: Ella, Raches, Siddharth Reddy, Harsh Jogdand, Vamshi Sarangi, Brunda Ganneru, Sai Prasad, Dipankar Das, Dugyala Raju, Usha Praturi, Gajanan Sapkal, Pragya Yadav, Prabhakar Reddy, Savita Verma, Chandramani Singh, Sagar Vivek Redkar, Chandra Sekhar…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-03-08
Description: BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine (3 μg or 6 μg) formulated with a toll-like receptor 7/8 agonist molecule (IMDG) adsorbed to alum (Algel). We previously reported findings from a double-blind, multicentre, randomised, controlled… -
Creator: Ella, Raches, Krishna Mohan Vadrevu, Harsh Jogdand, Sai Prasad, Siddharth Reddy, Vamshi Sarangi, Brunda Ganneru, Gajanan Sapkal, Pragya Yadav, Priya Abraham, Samiran Panda, Nivedita Gupta, Prabhakar Reddy, Savita Verma, Sanjay Kumar Rai, Chandramani…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-01-21
Description: To mitigate the effects of COVID-19, a vaccine is urgently needed. BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine formulated with a toll-like receptor 7/8 agonist molecule adsorbed to alum (Algel-IMDG) or alum (Algel).A response to this…