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Browse Items (140 total)
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Creator: the ACTT-1 Study Group Members
Subject: Research
Item Type: Publication
Date Last Updated: 2020-11-05
Description: We conducted a double-blind, randomized, placebo-controlled trial of intravenous remdesivir in adults who were hospitalized with Covid-19 and had evidence of lower respiratory tract infection.A response to this article was published:Dolin, Raphael,… -
Creator: Blair, P. W., M. G. Kortepeter, L. G. Downey, C. S. Madar, I. L. Downs, K. A. Martins, F. Rossi, J. A. Williams, A. Madar, C. W. Schellhase, J. J. Bearss, X. Zeng, S. Bavari, V. Soloveva, J. B. Wells, K. S. Stuthman, N. L. Garza, S. A. Vantongeren,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-25
Description: Ebola virus disease (EVD) supportive care strategies are largely guided by retrospective observational research. This study investigated the effect of EVD supportive care algorithms on duration of survival in a controlled nonhuman primate (NHP)… -
Creator: Karaba, Sara M., George Jones, Taylor Helsel, L. Leigh Smith, Robin Avery, Kathryn Dzintars, Alejandra B. Salinas, Sara C. Keller, Jennifer L. Townsend, Eili Klein, Joe Amoah, Brian T. Garibaldi, Sara E. Cosgrove, and Valeria Fabre.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-21
Description: Bacterial infections may complicate viral pneumonias. Recent reports suggest that bacterial co-infection at time of presentation is uncommon in coronavirus disease 2019 (COVID-19); however, estimates were based on microbiology tests alone. We sought… -
Creator: Strampe, Jamie, Danny A. Asogun, Emily Speranza, Meike Pahlmann, Ali Soucy, Sabrina Bockholt, Elisa Pallasch, Beate Becker-Ziaja, Sophie Duraffour, Nahid Bhadelia, Yemisi Ighodalo, Jennifer Oyakhilome, Emmanuel O. Omomoh, Thomas Olokor, Donatus I.…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-01-20
Description: Lassa fever is endemic in several west African countries. Case-fatality rates ranging from 21% to 69% have been reported. The pathophysiology of the disease in humans and determinants of mortality remain poorly understood. We aimed to determine host… -
Creator: the Ambulatory COVID Study Team
Subject: Research
Item Type: Publication
Date Last Updated: 2021-01-05
Description: Outpatient coronavirus disease 2019 (COVID-19) has been insufficiently characterized. To determine the progression of disease and determinants of hospitalization, we conducted a prospective cohort study. -
Creator: The REMAP-CAP Investigators
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. -
Creator: The RECOVERY Collaborative Group.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. -
Creator: PRINCIPLE Trial Collaborative Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-03-04
Description: Azithromycin, an antibiotic with potential antiviral and anti-inflammatory properties, has been used to treat COVID-19, but evidence from community randomised trials is lacking. We aimed to assess the effectiveness of azithromycin to treat suspected… -
Creator: Mbala-Kingebeni, Placide, Catherine Pratt, Mbusa Mutafali-Ruffin, Matthias G. Pauthner, Faustin Bile, Antoine Nkuba-Ndaye, Allison Black, Eddy Kinganda-Lusamaki, Martin Faye, Amuri Aziza, Moussa M. Diagne, Daniel Mukadi, Bailey White, James Hadfield,…
Subject: Research
Item Type: Publication
Description: During the 2018–2020 Ebola virus disease (EVD) outbreak in North Kivu province in the Democratic Republic of Congo, EVD was diagnosed in a patient who had received the recombinant vesicular stomatitis virus–based vaccine expressing a ZEBOV… -
Creator: Peart Akindele, Nadine, Theodore Kouo, Andrew H. Karaba, Oren Gordon, Katherine Z. J. Fenstermacher, Jeanette Beaudry, Jessica H. Rubens, Christine C. Atik, Weiqiang Zhou, Hongkai Ji, Xueting Tao, Dhananjay Vaidya, Heba Mostafa, Patrizio Caturegli,…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-05-24
Description: Multisystem Inflammatory Syndrome in Children (MIS-C) is a severe clinical phenotype of SARS-CoV-2 infection that remains poorly understood.