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Browse Items (73 total)
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Creator: FDA
Subject: Research
Item Type: Hyperlink
Date Last Updated: 2023-05-12
Description: The Emergency Use Authorization (EUA) authority allows FDA to help strengthen the nation’s public health protections against chemical, biological, radiological, and nuclear (CBRN) threats including infectious diseases, by facilitating the… -
Creator: Mengfei Chen, Wenjuan Shen, Nicholas R. Rowan, Heather Kulaga, Alexander Hillel, Murugappan Ramanathan Jr, and Andrew P. Lane.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: ACE2 protein is expressed at high levels in the human olfactory epithelium relative to upper airway epithelial cells. This may explain COVID-19-associated olfactory dysfunction, while suggesting a SARS-CoV-2 reservoir site and potential intranasal… -
Creator: Ward, Brian J., Alexander Makarkov, Annie Séguin, Stéphane Pillet, Sonia Trépanier, Jiwanjeet Dhaliwall, Michael D. Libman, Timo Vesikari, and Nathalie Landry.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-10-13
Description: Seasonal influenza remains a substantial public health threat despite the availability of egg-derived and other vaccines. Plant-based manufacturing might address some of the limitations of current vaccines. We describe two phase 3 efficacy studies of… -
Creator: Young, Barnaby E., Siew-Wai Fong, Yi-Hao Chan, Tze-Minn Mak, Li Wei Ang, Danielle E. Anderson, Cheryl Yi-Pin Lee, Siti Naqiah Amrun, Bernett Lee, Yun Shan Goh, Yvonne C. F. Su, Wycliffe E. Wei, Shirin Kalimuddin, Louis Yi Ann Chai, Surinder Pada,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with a 382-nucleotide deletion (∆382) in the open reading frame 8 (ORF8) region of the genome have been detected in Singapore and other countries. We investigated the effect of… -
Creator: Brenner, Daniel S., Gigi Y. Liu, Rodney Omron, Olive Tang, Brian T. Garibaldi, and Tiffany C. Fong.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-03-01
Description: As medical infrastructures are strained by SARS-CoV-2, rapid and accurate screening tools are essential. In portions of the world, reverse transcription polymerase chain reaction (RT-PCR) testing remains slow and in limited supply, and computed… -
Creator: Abigail E Lowe, Colleen Kraft, Mark G Kortepeter, Keith F Hansen, Kristine Sanger, Ann Johnson, Jonathan D Grein, Julie Martin, Rebecca Rousselle, Jennifer A Garland, Jessica Spotts, John J Lowe, Lauren M Sauer, Christopher J Kratochvil, Bruce G…
Subject: Research
Item Type: Publication
Date Last Updated: 2022-05-31
Description: Research is foundational for evidence-based management of patients. Clinical research, however, takes time to plan, conduct, and disseminate—a luxury that is rarely available during a public health emergency. The University of Nebraska Medical Center… -
Creator: Angela Vasa, Valerie Pacino, Sami Vasistha, Wael ElRayes, John J Lowe
Subject: Emergency Response
Item Type: Publication
Date Last Updated: 2022-05-31
Description: In February 2015, the US Department of Health and Human Services developed a tiered hospital network to deliver safe and effective care to patients with Ebola virus disease (EVD) and other special pathogens. The tiered network consisted of regional… -
Creator: Agostini, Maria, Erica Andres, Amy Sims, Rachel Graham, Timothy Sheahan, Xiaotao Lu, Everett Smith, James Case, Joy Feng, Robert Jordan, Adrian Ray, Tomas Cihlar, Dustin Siegel, Richard Mackman, Michael Clarke, Ralph Baric, and Mark Denison.
Subject: Research
Item Type: Publication
Date Last Updated: 2018-03
Description: Emerging coronaviruses (CoVs) cause severe disease in humans, but no approved therapeutics are available. -
Creator: Jonathan D Grein, Jennifer A Garland, Christa Arguinchona, Maria G Frank, Brian T Garibaldi, Amanda Grindle, Angela Hewlett, Susan Kline, Corri B Levine, Aneesh Mehta, Vikramjit Mukherjee, Lauren M Sauer, Eileen F Searle, Sharon Vanairsdale, Angela…
Subject: Emergency Management
Item Type: Publication
Date Last Updated: 2022-05-31
Description: The National Emerging Special Pathogens Training and Education Center (NETEC) was established in 2015 to improve the capabilities of healthcare facilities to provide safe and effective care to patients with Ebola and other special pathogens in the… -
Creator: Grassly, Nicholas C., Margarita Pons-Salort, Edward P. K. Parker, Peter J. White, Neil M. Ferguson, Kylie Ainslie, Marc Baguelin, Samir Bhatt, Adhiratha Boonyasiri, Nick Brazeau, Lorenzo Cattarino, Helen Coupland, Zulma Cucunuba, Gina…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: WHO has called for increased testing in response to the COVID-19 pandemic, but countries have taken different approaches and the effectiveness of alternative strategies is unknown. We aimed to investigate the potential impact of different testing and…