Navegar por los elementos (60 total)

• Recent successes in therapeutics for Ebola virus disease: no time for complacency

  Etiquetas Ebola, R-Res&Pub, Therapeutics, Viral Hemorrhagic Fever
  Autor: Iversen, Patrick L., Christopher D. Kane, Xiankun Zeng, Rekha G. Panchal, Travis K. Warren, Sheli R. Radoshitzky, Jens H. Kuhn, Rajini R. Mudhasani, Christopher L. Cooper, Amy C. Shurtleff, Farooq Nasar, Melek M. E. Sunay, Allen J. Duplantier, Brett…
  Tema: Research
  Tipo de elemento: Publicación
  Fecha de actualización: 2020-06-18
  Descripción: The PALM trial in the Democratic Republic of the Congo identified a statistically significant survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute Ebola virus disease; however, substantial gaps remain in improving…

• Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in children in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial

  Etiquetas Ebola, Pediatrics, R-Res&Pub, R-SP, Therapeutics, Vaccine Study, Viral Hemorrhagic Fever
  Autor: Tapia, Milagritos D., Samba O. Sow, Khardiata D. Mbaye, Aliou Thiongane, Birahim P. Ndiaye, Cheikh T. Ndour, Souleymane Mboup, Babajide Keshinro, Thompson N. Kinge, Guy Vernet, Jean Joel Bigna, Stephen Oguche, Kwadwo A. Koram, Kwaku P. Asante,…
  Tema: Research
  Tipo de elemento: Publicación
  Fecha de actualización: 2020-03-19
  Descripción: During the large 2013–16 Ebola virus outbreak caused by the Zaire Ebola virus, about 20% of cases were reported in children. This study is the first, to our knowledge, to evaluate an Ebola vaccine in children younger than 6 years.

• Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in adults in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial

  Etiquetas Ebola, R-Res&Pub, Therapeutics, Vaccine Study, Viral Hemorrhagic Fever
  Autor: Tapia, Milagritos D., Samba O. Sow, Birahim P. Ndiaye, Khardiata D. Mbaye, Aliou Thiongane, Cheikh T. Ndour, Souleymane Mboup, Julie A. Ake, Babajide Keshinro, Gideon A. Akintunde, Thompson N. Kinge, Guy Vernet, Jean Joel Bigna, Stephen Oguche,…
  Tema: Research
  Tipo de elemento: Publicación
  Fecha de actualización: 2020-03-19
  Descripción: The 2014 Zaire Ebola virus disease epidemic accelerated vaccine development for the virus.

• Chimpanzee adenovirus type 3 vectored Ebola vaccine: expanding the field

  Etiquetas Ebola, R-Res&Pub, Therapeutics, Vaccine Study, Viral Hemorrhagic Fever
  Autor: Bavari, Sina, and Patrick L. Iversen.
  Tema: Research
  Tipo de elemento: Publicación
  Fecha de actualización: 2020-03-19
  Descripción: Two phase 2 randomised clinical trials evaluating ChAd3-EBO-Z administered to healthy adults in Cameroon, Mali, Nigeria, and Senegal and healthy children in Mali and Senegal are reported by Milagritos Tapia and colleagues in The Lancet Infectious…
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  Bioaerosol sampling for the detection of aerosolized influenza virus

  Etiquetas Airborne Transmission, Flu, Infection Prevention and Control, Influenza, R-Res&Pub, Therapeutics
  Autor: Blachere, Francoise M., William G. Lindsley, James E. Slaven, Brett J. Green, Stacey E. Anderson, Bean T. Chen, and Don H. Beezhold.
  Tema: Research
  Tipo de elemento: Publicación
  Fecha de actualización: 2007-05
  Descripción: A Collison single-jet nebulizer was used to aerosolize the attenuated FluMist vaccine into a calm-air settling chamber.
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  First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease.

  Etiquetas Neonates, Pediatrics, R-Res&Pub, R-SP, R-T&C, Survivors, Therapeutics, Treatment and Care
  Autor: Dörnemann, Jenny, Chiara Burzio, Axelle Ronsse, Armand Sprecher, Hilde De Clerck, Michel Van Herp, Marie-Claire Kolié, Vesselina Yosifiva, Severine Caluwaerts, Anita K. McElroy, and Annick Antierens.
  Tema: Treatment & Care
  Tipo de elemento: Publicación
  Fecha de actualización: 2017-01-15
  Descripción: A neonate born to an Ebola virus-positive woman was diagnosed with Ebola virus infection on her first day of life.

• Corporate Report: Secure Specimen Transfer from Ebola Biobank to the UK (United Kingdom)

  Etiquetas Ebola, R-Res&Pub, Specimen Transport, Therapeutics, Vaccine Study
  Autor: United Kingdom Department of Health (DH)
  Tema: Research
  Tipo de elemento: Guía
  Fecha de actualización: 2019-07-19
  Descripción: This report summarizes the establishment of the Ebola Biobank, its governance, and how materials were safely transported in 2015 from West Africa to the United Kingdom for curation by Public Health England. The Biobank is a secure but accessible…

• Independent monitoring board recommends early termination of Ebola therapeutics trial in DRC because of favorable results with two of four candidates

  Etiquetas Ebola, R-Res&Pub, Therapeutics
  Autor: NIH
  Tema: Research
  Tipo de elemento: Hipervínculo
  Fecha de actualización: 2019-08-12
  Descripción: The Pamoja Tulinde Maisha (PALM [together save lives]) study is a randomized, controlled trial of four investigational agents (ZMapp, remdesivir, mAb114 and REGN-EB3) for the treatment of patients with Ebola virus disease. The study began on Nov. 20,…

• Ebola therapies: an unconventionally calculated risk.

  Etiquetas Clinical Trial, Ebola, Outbreaks, R-Res&Pub, Therapeutics, Vaccine Study
  Autor: Fallah MP, Skrip LA.
  Tema: Research
  Tipo de elemento: Publicación
  Fecha de actualización: 2019-01-24
  Descripción: This article reviews the testing of Ebola therapies during the outbreak.

• Preliminary results on the efficacy of rVSV-ZEBOV-GP Ebola vaccine using the ring vaccination strategy in the control of an Ebola outbreak in the Democratic Republic of the Congo: an example of integration of research into epidemic response.

  Etiquetas Clinical Trial, Ebola, Epidemic, Outbreaks, R-Res&Pub, R-T&C, Research, Research Design, Therapeutics, Vaccine Study
  Autor: WHO
  Tema: Infection Control
  Tipo de elemento: Publicación
  Fecha de actualización: 2019-04-12
  Descripción: ABOUT THIS ANALYSIS: DRC’s national research institute, the Institut National pour la Recherche Biomedicale (INRB) and WHO have conducted a preliminary analysis of the data being collected from the ring vaccination protocol. The analysis summarized…