Development of a Pediatric Ebola Predictive Score, Sierra Leone
Contenu
Click for External Resource*
Click to read full article*
*The link above may share a zip file (.zip) hosted on repository.netecweb.org. Zip files will download automatically.
*All other links are external and will open in a new window. If you click an external link, you are leaving the NETEC site, and we do not maintain, review, or endorse these materials. See our terms of use.
Item Type
PublicationTerms of Use
By accessing these materials you are agreeing to our terms of use, which may be found here: Terms of Use.
Titre
Development of a Pediatric Ebola Predictive Score, Sierra Leone
Sujet
Description
We compared children who were positive for Ebola virus disease (EVD) with those who were negative to derive a pediatric EVD predictor (PEP) score.
Date
2018-02
Type
Citer ce document
Fitzgerald, F., Wing, K., Naveed, A., Gbessay, M., Ross, J., Checchi, F....Yeung, S. 2018. Development of a Pediatric Ebola Predictive Score, Sierra Leone. Emerging Infectious Diseases, 24(2), 311-319. https://dx.doi.org/10.3201/eid2402.171018.
Résumé
We compared children who were positive for Ebola virus disease (EVD) with those who were negative to derive a pediatric EVD predictor (PEP) score. We collected data on all children <13 years of age admitted to 11 Ebola holding units in Sierra Leone during August 2014-March 2015 and performed multivariable logistic regression. Among 1,054 children, 309 (29%) were EVD positive and 697 (66%) EVD negative, with 48 (5%) missing. Contact history, conjunctivitis, and age were the strongest positive predictors for EVD. The PEP score had an area under receiver operating characteristics curve of 0.80. A PEP score of 7/10 was 92% specific and 44% sensitive; 3/10 was 30% specific, 94% sensitive. The PEP score could correctly classify 79%-90% of children and could be used to facilitate triage into risk categories, depending on the sensitivity or specificity required.
Accessibilité
Free online.
Was this resource helpful?