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Browse Items (1478 total)
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Creator: Manisty, Charlotte, Ashley D. Otter, Thomas A. Treibel, Áine McKnight, Daniel M. Altmann, Timothy Brooks, Mahdad Noursadeghi, Rosemary J. Boyton, Amanda Semper, and James C. Moon.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: Rapid vaccine-induced population immunity is a key global strategy to control COVID-19. Vaccination programmes must maximise early impact, particularly with accelerated spread of new variants. -
Creator: Prendecki, Maria, Candice Clarke, Jonathan Brown, Alison Cox, Sarah Gleeson, Mary Guckian, Paul Randell, Alessia Dalla Pria, Liz Lightstone, Xiao-Ning Xu, Wendy Barclay, Stephen P. McAdoo, Peter Kelleher, and Michelle Willicombe.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: The rapid implementation of SARS-CoV-2 vaccination is now a global health-care priority. Successful phase 3 trial outcomes have been reported for numerous vaccines that induce robust humoral and cellular immune responses against the SARS-CoV-2 spike… -
Creator: The RECOVERY Collaborative Group.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. -
Creator: The REMAP-CAP Investigators
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. -
Creator: Dagan, Noa, Noam Barda, Eldad Kepten, Oren Miron, Shay Perchik, Mark A. Katz, Miguel A. Hernán, Marc Lipsitch, Ben Reis, and Ran D. Balicer.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-24
Description: As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse populations in a noncontrolled setting. In this study, data from Israel’s… -
Creator: the Oxford COVID Vaccine Trial Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-19
Description: The ChAdOx1 nCoV-19 (AZD1222) vaccine has been approved for emergency use by the UK regulatory authority, Medicines and Healthcare products Regulatory Agency, with a regimen of two standard doses given with an interval of 4–12 weeks. -
Creator: The Medical Countermeasures Working Group of the National Emerging Special Pathogens Training and Education Center’s (NETEC’s) Special Pathogens Research Network (SPRN)
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2021-02-18
Description: This article is one of a series on acute, severe diseases of humans caused by emerging viruses for which there are no or limited licensed medical countermeasures. We approached this summary on South American Hemorrhagic Fevers (SAHF) from a clinical… -
Creator: the PlasmAr Study Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-18
Description: Convalescent plasma is frequently administered to patients with Covid-19 and has been reported, largely on the basis of observational data, to improve clinical outcomes. Minimal data are available from adequately powered randomized, controlled… -
Creator: the Fundación INFANT–COVID-19 Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-18
Description: Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered earlier… -
Creator: Wu, Kai, Anne P. Werner, Matthew Koch, Angela Choi, Elisabeth Narayanan, Guillaume B. E. Stewart-Jones, Tonya Colpitts, Hamilton Bennett, Seyhan Boyoglu-Barnum, Wei Shi, Juan I. Moliva, Nancy J. Sullivan, Barney S. Graham, Andrea Carfi, Kizzmekia S.…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-17
Description: The mRNA-1273 vaccine against SARS-CoV-2 elicited high neutralizing-antibody titers in phase 1 trial participants and has been shown to be highly efficacious in preventing symptomatic Covid-19 disease and severe disease.