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Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever

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Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Feverhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682919/pdf/nihms904566.pdf
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Title
Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever
Subject
Treatment & Care
Description
Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir.
Creator
Raabe, V. N., G. Kann, B. S. Ribner, A. Morales, J. B. Varkey, A. K. Mehta, G. M. Lyon, S. Vanairsdale, K. Faber, S. Becker, M. Eickmann, T. Strecker, S. Brown, K. Patel, P. De Leuw, G. Schuettfort, C. Stephan, H. Rabenau, J. D. Klena, P. E. Rollin, A. McElroy, U. Stroher, S. Nichol, C. S. Kraft, T. Wolf and U. Emory Serious Communicable Diseases
Date
2017-09-01
Citation
Raabe, V. N., G. Kann, B. S. Ribner, A. Morales, J. B. Varkey, A. K. Mehta, G. M. Lyon, S. Vanairsdale, K. Faber, S. Becker, M. Eickmann, T. Strecker, S. Brown, K. Patel, P. De Leuw, G. Schuettfort, C. Stephan, H. Rabenau, J. D. Klena, P. E. Rollin, A. McElroy, U. Stroher, S. Nichol, C. S. Kraft, T. Wolf and U. Emory Serious Communicable Diseases (2017). "Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever." Clin Infect Dis 65(5): 855-859.
Abstract
Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir. Both patients survived but developed transaminitis and had prolonged detectable virus RNA in blood and semen, suggesting that the possibility of sexual transmission of Lassa virus should be considered.
Accessibility
free online - Pubmed Central
URL
https://www.ncbi.nlm.nih.gov/pubmed/29017278
Read Online
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682919/
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