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- Query: COVID
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| Record Type | Title | Thumbnail | Subject | Date Published | Description |
|---|---|---|---|---|---|
| Item |
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Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia | Research | 2020-09-21 | We developed a heterologous COVID-19 vaccine consisting of two components, a recombinant adenovirus type 26 (rAd26) vector and a recombinant adenovirus type 5 (rAd5) vector, both carrying the gene for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein (rAd26-S and… |
| Item | Estimating the infection-fatality risk of SARS-CoV-2 in New York City during the spring 2020 pandemic wave: a model-based analysis | Research | 2020-10-19 | As the COVID-19 pandemic continues to unfold, the infection-fatality risk (ie, risk of death among all infected individuals including those with asymptomatic and mild infections) is crucial for gauging the burden of death due to COVID-19 in the coming months or years. Here, we estimate the… | |
| Item | Inpatient COVID-19 Outcomes in Solid Organ Transplant Recipients Compared to Non-Solid Organ Transplant Patients: A Retrospective Cohort | Research | 2020-12-07 | Immunosuppression and comorbidities might place solid organ transplant (SOT) recipients at higher risk from COVID-19, as suggested by recent case series. We compared 45 SOT vs 2427 non-SOT patients who were admitted with COVID-19 to our health-care system (3/1/20-8/21/20), evaluating hospital… | |
| Item | Bioaerosol sampling for SARS-CoV-2 in a referral center with critically ill COVID-19 patients March-May 2020 | Research | 2021-01-28 | Background: Previous research has shown that rooms of patients with COVID-19 present the potential for healthcare-associated transmission through aerosols containing SARS-CoV-2. However, data on the presence of these aerosols outside of patient rooms are limited. We investigated whether… | |
| Item | Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults | Research | 2021-02-18 | Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered earlier in the course of illness. | |
| Item | Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19 | Research | 2021-02-26 | The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state, leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic complications, among other sequelae. Statins, which are known to have anti-inflammatory and antithrombotic properties, have been… | |
| Item | Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia | Treatment & Care | 2021-04-22 | Coronavirus disease 2019 (Covid-19) is associated with immune dysregulation and hyperinflammation, including elevated interleukin-6 levels. The use of tocilizumab, a monoclonal antibody against the interleukin-6 receptor, has resulted in better outcomes in patients with severe Covid-19 pneumonia in… | |
| Item | Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients | Laboratory | 2020-06-23 | SARS-CoV-2, the virus responsible for COVID-19, is causing a devastating worldwide pandemic, and there is a pressing need to understand the development, specificity, and neutralizing potency of humoral immune responses during acute infection. We report a cross-sectional study of antibody responses… | |
| Item | Connecting clusters of COVID-19: an epidemiological and serological investigation | Laboratory | 2020-04-21 | Elucidation of the chain of disease transmission and identification of the source of coronavirus disease 2019 (COVID-19) infections are crucial for effective disease containment. | |
| Item | The Utility and Sustainability of US Ebola Treatment Centers during the COVID-19 Pandemic | Research | 2022-02-22 | In response to the 2014-2016 West Africa Ebola virus disease (EVD) epidemic, the Centers for Disease Control and Prevention (CDC) designated 56 US hospitals as Ebola treatment centers (ETCs) with high-level isolation capabilities. We aimed to determine ongoing sustainability of ETCs and identify how… |