Acute, Generalized Vesicular or Pustular Rash Illness Testing Protocol in the United States

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Title

Acute, Generalized Vesicular or Pustular Rash Illness Testing Protocol in the United States

Description

This protocol has been developed to guide the sequence and type of laboratory testing to be undertaken in situations involving specimens from patients with acute, generalized vesicular or pustular rash illness, or suspected smallpox vaccine (vaccinia virus) adverse event

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Date Last Updated (Year-Month-Day)

2016-12-01

Objectives

Introduction

This protocol has been developed to guide the sequence and type of laboratory testing to be undertaken in situations involving specimens from patients with acute, generalized vesicular or pustular rash illness, or suspected smallpox vaccine (vaccinia virus) adverse event. This protocol may also be followed to test environmental specimens which may contain an Orthopoxvirus. The testing protocol includes four flowchart diagrams, each illustrating a different testing circumstance. The protocol has been designed for use alongside the Centers for Disease Control and Prevention’s clinical assessment tool, Evaluating Patients for Smallpox: Acute, Generalized Vesicular or Pustular Rash Illness Protocol. The laboratory testing protocol is designed to address testing needs in a pre-event setting, when no poxvirus emergency has been detected or declared. In the event of a smallpox (variola virus) outbreak, critical updates will be announced by the Laboratory Response Network (LRN).

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Free CDC guidance document