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Vaccine innovation spurred by the long wait for an Ebola virus vaccine
The 2013–16 Ebola virus outbreak—the largest ever recorded—substantially hastened the development of an Ebola virus vaccine. Before this outbreak, the safety and immunogenicity of only two Ebola virus vaccine candidates (a DNA-based vaccine and a recombinant adenovirus [rAd] serotype 5-based vaccine) had been evaluated in phase 1 clinical trials.
Date Last Updated (Year-Month-Day)
Fausther-Bovendo, Hugues, and Gary Kobinger. 2020. "Vaccine innovation spurred by the long wait for an Ebola virus vaccine." The Lancet Infectious Diseases.
Free online on Lancet site.