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Browse Items (1478 total)
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Creator: Logunov, Denis Y., Inna V. Dolzhikova, Dmitry V. Shcheblyakov, Amir I. Tukhvatulin, Olga V. Zubkova, Alina S. Dzharullaeva, Anna V. Kovyrshina, Nadezhda L. Lubenets, Daria M. Grousova, Alina S. Erokhova, Andrei G. Botikov, Fatima M. Izhaeva, Olga…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-02
Description: A heterologous recombinant adenovirus (rAd)-based vaccine, Gam-COVID-Vac (Sputnik V), showed a good safety profile and induced strong humoral and cellular immune responses in participants in phase 1/2 clinical trials. Here, we report preliminary… -
Creator: Richmond, Peter, Lara Hatchuel, Min Dong, Brenda Ma, Branda Hu, Igor Smolenov, Ping Li, Peng Liang, Htay Htay Han, Joshua Liang, and Ralf Clemens.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-01-29
Description: As part of the accelerated development of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we report a dose-finding and adjuvant justification study of SCB-2019, a protein subunit vaccine candidate containing a… -
Creator: Kim, Min-Chul, Chunguang Cui, Kyeong-Ryeol Shin, Joon-Yong Bae, Oh-Joo Kweon, Mi-Kyung Lee, Seong-Ho Choi, Sun-Young Jung, Man-Seong Park, and Jin-Won Chung.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-01-27
Description: The duration of transmissibility of coronavirus disease 2019 (Covid-19) and the associated level of contagion have been uncertain. We cultured severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in serial respiratory samples obtained from… -
Creator: Ella, Raches, Krishna Mohan Vadrevu, Harsh Jogdand, Sai Prasad, Siddharth Reddy, Vamshi Sarangi, Brunda Ganneru, Gajanan Sapkal, Pragya Yadav, Priya Abraham, Samiran Panda, Nivedita Gupta, Prabhakar Reddy, Savita Verma, Sanjay Kumar Rai, Chandramani…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-01-21
Description: To mitigate the effects of COVID-19, a vaccine is urgently needed. BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine formulated with a toll-like receptor 7/8 agonist molecule adsorbed to alum (Algel-IMDG) or alum (Algel).A response to this… -
Creator: Strampe, Jamie, Danny A. Asogun, Emily Speranza, Meike Pahlmann, Ali Soucy, Sabrina Bockholt, Elisa Pallasch, Beate Becker-Ziaja, Sophie Duraffour, Nahid Bhadelia, Yemisi Ighodalo, Jennifer Oyakhilome, Emmanuel O. Omomoh, Thomas Olokor, Donatus I.…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-01-20
Description: Lassa fever is endemic in several west African countries. Case-fatality rates ranging from 21% to 69% have been reported. The pathophysiology of the disease in humans and determinants of mortality remain poorly understood. We aimed to determine host… -
Creator: Andersen, Kathleen M., Hemalkumar B. Mehta, Natasha Palamuttam, Daniel Ford, Brian T. Garibaldi, Paul G. Auwaerter, Jodi Segal, and G. Caleb Alexander.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-01-07
Description: It is unclear whether chronic use of immunosuppressive drugs worsens or improves the severity of coronavirus disease 2019 (COVID-19), with plausible mechanisms for both. -
Creator: Karaba, Sara M., George Jones, Taylor Helsel, L. Leigh Smith, Robin Avery, Kathryn Dzintars, Alejandra B. Salinas, Sara C. Keller, Jennifer L. Townsend, Eili Klein, Joe Amoah, Brian T. Garibaldi, Sara E. Cosgrove, and Valeria Fabre.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-21
Description: Bacterial infections may complicate viral pneumonias. Recent reports suggest that bacterial co-infection at time of presentation is uncommon in coronavirus disease 2019 (COVID-19); however, estimates were based on microbiology tests alone. We sought… -
Creator: Blair, P. W., M. G. Kortepeter, L. G. Downey, C. S. Madar, I. L. Downs, K. A. Martins, F. Rossi, J. A. Williams, A. Madar, C. W. Schellhase, J. J. Bearss, X. Zeng, S. Bavari, V. Soloveva, J. B. Wells, K. S. Stuthman, N. L. Garza, S. A. Vantongeren,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-25
Description: Ebola virus disease (EVD) supportive care strategies are largely guided by retrospective observational research. This study investigated the effect of EVD supportive care algorithms on duration of survival in a controlled nonhuman primate (NHP)… -
Creator: Sridhar V Basavaraju, Monica E Patton, Kacie Grimm, Mohammed Ata Ur Rasheed, Sandra Lester, Lisa Mills, Megan Stumpf, Brandi Freeman, Azaibi Tamin, Jennifer Harcourt, Jarad Schiffer, Vera Semenova, Han Li, Bailey Alston, Muyiwa Ategbole, Shanna…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-11-30
Description: SARS-CoV-2, the virus that causes COVID-19 disease, was first identified in Wuhan, China in December 2019, with subsequent worldwide spread. The first U.S. cases were identified in January 2020. -
Creator: Keech, Cheryl, Gary Albert, Iksung Cho, Andreana Robertson, Patricia Reed, Susan Neal, Joyce S. Plested, Mingzhu Zhu, Shane Cloney-Clark, Haixia Zhou, Gale Smith, Nita Patel, Matthew B. Frieman, Robert E. Haupt, James Logue, Marisa McGrath, Stuart…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-10
Description: NVX-CoV2373 is a recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) nanoparticle vaccine composed of trimeric full-length SARS-CoV-2 spike glycoproteins and Matrix-M1 adjuvant.