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Browse Items (717 total)
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Creator: the GS-US-540-5773 Investigators
Subject: Research
Item Type: Publication
Date Last Updated: 2020-11-05
Description: We conducted a randomized, open-label, phase 3 trial involving hospitalized patients with confirmed SARS-CoV-2 infection, oxygen saturation of 94% or less while they were breathing ambient air, and radiologic evidence of pneumonia. -
Creator: the ACTT-1 Study Group Members
Subject: Research
Item Type: Publication
Date Last Updated: 2020-11-05
Description: We conducted a double-blind, randomized, placebo-controlled trial of intravenous remdesivir in adults who were hospitalized with Covid-19 and had evidence of lower respiratory tract infection.A response to this article was published:Dolin, Raphael,… -
Creator: Gudbjartsson, Daniel F., Gudmundur L. Norddahl, Pall Melsted, Kristbjorg Gunnarsdottir, Hilma Holm, Elias Eythorsson, Asgeir O. Arnthorsson, Dadi Helgason, Kristbjorg Bjarnadottir, Ragnar F. Ingvarsson, Brynja Thorsteinsdottir, Steinunn…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-29
Description: Little is known about the nature and durability of the humoral immune response to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). -
Creator: Ng, Oon Tek, Kalisvar Marimuthu, Vanessa Koh, Junxiong Pang, Kyaw Zaw Linn, Jie Sun, Liang De Wang, Wan Ni Chia, Charles Tiu, Monica Chan, Li Min Ling, Shawn Vasoo, Mohammad Yazid Abdad, Po Ying Chia, Tau Hong Lee, Ray Junhao Lin, Sapna P.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-11-02
Description: The proportion of asymptomatic carriers and transmission risk factors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among household and non-household contacts remains unclear. -
Creator: Stone, John H., Matthew J. Frigault, Naomi J. Serling-Boyd, Ana D. Fernandes, Liam Harvey, Andrea S. Foulkes, Nora K. Horick, Brian C. Healy, Ruta Shah, Ana Maria Bensaci, Ann E. Woolley, Sarah Nikiforow, Nina Lin, Manish Sagar, Harry Schrager, David…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-21
Description: The efficacy of interleukin-6 receptor blockade in hospitalized patients with coronavirus disease 2019 (Covid-19) who are not receiving mechanical ventilation is unclear. -
Creator: Yang, Wan, Sasikiran Kandula, Mary Huynh, Sharon K. Greene, Gretchen Van Wye, Wenhui Li, Hiu Tai Chan, Emily McGibbon, Alice Yeung, Don Olson, Anne Fine, and Jeffrey Shaman.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-19
Description: As the COVID-19 pandemic continues to unfold, the infection-fatality risk (ie, risk of death among all infected individuals including those with asymptomatic and mild infections) is crucial for gauging the burden of death due to COVID-19 in the… -
Creator: Walsh, Edward E., Robert W. Frenck, Ann R. Falsey, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen Lockhart, Kathleen Neuzil, Mark J. Mulligan, Ruth Bailey, Kena A. Swanson, Ping Li, Kenneth Koury, Warren Kalina, David Cooper, Camila…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-14
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and the resulting disease, coronavirus disease 2019 (Covid-19), have spread to millions of persons worldwide. Multiple vaccine candidates are under development, but no vaccine is… -
Creator: Xia, Shengli, Yuntao Zhang, Yanxia Wang, Hui Wang, Yunkai Yang, George Fu Gao, Wenjie Tan, Guizhen Wu, Miao Xu, Zhiyong Lou, Weijin Huang, Wenbo Xu, Baoying Huang, Huijuan Wang, Wei Wang, Wei Zhang, Na Li, Zhiqiang Xie, Ling Ding, Wangyang You, Yuxiu…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-15
Description: The ongoing COVID-19 pandemic warrants accelerated efforts to test vaccine candidates. We aimed to assess the safety and immunogenicity of an inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidate, BBIBP-CorV, in… -
Creator: Ward, Brian J., Alexander Makarkov, Annie Séguin, Stéphane Pillet, Sonia Trépanier, Jiwanjeet Dhaliwall, Michael D. Libman, Timo Vesikari, and Nathalie Landry.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-10-13
Description: Seasonal influenza remains a substantial public health threat despite the availability of egg-derived and other vaccines. Plant-based manufacturing might address some of the limitations of current vaccines. We describe two phase 3 efficacy studies of… -
Creator: Poland, Gregory A., Inna G. Ovsyannikova, and Richard B. Kennedy.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-10-13
Description: Understanding immune responses to severe acute respiratory syndrome coronavirus 2 is crucial to understanding disease pathogenesis and the usefulness of bridge therapies, such as hyperimmune globulin and convalescent human plasma, and to developing…