Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever
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Titre
Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever
Sujet
Description
Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir.
Date
2017-09-01
Type
Citer ce document
Raabe, V. N., G. Kann, B. S. Ribner, A. Morales, J. B. Varkey, A. K. Mehta, G. M. Lyon, S. Vanairsdale, K. Faber, S. Becker, M. Eickmann, T. Strecker, S. Brown, K. Patel, P. De Leuw, G. Schuettfort, C. Stephan, H. Rabenau, J. D. Klena, P. E. Rollin, A. McElroy, U. Stroher, S. Nichol, C. S. Kraft, T. Wolf and U. Emory Serious Communicable Diseases (2017). "Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever." Clin Infect Dis 65(5): 855-859.
Résumé
Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir. Both patients survived but developed transaminitis and had prolonged detectable virus RNA in blood and semen, suggesting that the possibility of sexual transmission of Lassa virus should be considered.
Accessibilité
free online - Pubmed Central
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