Development of a Pediatric Ebola Predictive Score, Sierra Leone
Elemento
Click for External Resource*
Click to read full article*
*The link above may share a zip file (.zip) hosted on repository.netecweb.org. Zip files will download automatically.
*All other links are external and will open in a new window. If you click an external link, you are leaving the NETEC site, and we do not maintain, review, or endorse these materials. See our terms of use.
Item Type
PublicaciónTerms of Use
By accessing these materials you are agreeing to our terms of use, which may be found here: Terms of Use.
Título
Development of a Pediatric Ebola Predictive Score, Sierra Leone
Materia
Descripción
We compared children who were positive for Ebola virus disease (EVD) with those who were negative to derive a pediatric EVD predictor (PEP) score.
Fecha
2018-02
Tipo
Citación
Fitzgerald, F., Wing, K., Naveed, A., Gbessay, M., Ross, J., Checchi, F....Yeung, S. 2018. Development of a Pediatric Ebola Predictive Score, Sierra Leone. Emerging Infectious Diseases, 24(2), 311-319. https://dx.doi.org/10.3201/eid2402.171018.
Resumen
We compared children who were positive for Ebola virus disease (EVD) with those who were negative to derive a pediatric EVD predictor (PEP) score. We collected data on all children <13 years of age admitted to 11 Ebola holding units in Sierra Leone during August 2014-March 2015 and performed multivariable logistic regression. Among 1,054 children, 309 (29%) were EVD positive and 697 (66%) EVD negative, with 48 (5%) missing. Contact history, conjunctivitis, and age were the strongest positive predictors for EVD. The PEP score had an area under receiver operating characteristics curve of 0.80. A PEP score of 7/10 was 92% specific and 44% sensitive; 3/10 was 30% specific, 94% sensitive. The PEP score could correctly classify 79%-90% of children and could be used to facilitate triage into risk categories, depending on the sensitivity or specificity required.
Accesibilidad
Free online.
Was this resource helpful?