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Monkeypox transmission following exposure in healthcare facilities in nonendemic settings: Low risk but limited literature

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Title

Monkeypox transmission following exposure in healthcare facilities in nonendemic settings: Low risk but limited literature

Description

Transmission risk of monkeypox in healthcare settings outside endemic regions has not been well defined. A rapid review of the literature, including cases outside monkeypox-endemic regions from 2000 to 2022 identified a single reported case of transmission. Available literature is limited by nonstandardized exposure definitions and limited detail describing exposures.

Date

2022-06-09

Citation

Zachary, K. C., and E. S. Shenoy. 2022. "Monkeypox transmission following exposure in healthcare facilities in nonendemic settings: Low risk but limited literature." Infect Control Hosp Epidemiol 43 (7):920-924. doi: 10.1017/ice.2022.152.

Abstract

Transmission risk of monkeypox in healthcare settings outside endemic regions has not been well defined. A rapid review of the literature, including cases outside monkeypox-endemic regions from 2000 to 2022 identified a single reported case of transmission. Available literature is limited by nonstandardized exposure definitions and limited detail describing exposures. The current monkeypox outbreak in multiple countries outside endemic regions has highlighted the limited knowledge of risk of transmission from infected patients in healthcare settings to others, including patients and healthcare personnel (HCP). Understanding the risk of transmission, and specifically the types of exposures in healthcare settings that may confer higher risk, is essential for infection prevention and control strategies, as well as to inform recommendations for postexposure monitoring and postexposure prophylaxis (PEP). Transmission to HCP in endemic settings is well described (Reference Nakoune, Lampaert and Ndjapou1,Reference Beer and Rao2), but to date it appears to be rare in well-resourced settings. In this rapid literature review, we identified published studies of cases of monkeypox outside endemic regions where nosocomial exposure was described. We found a single documented transmission event; however, variable definition of exposure and limited specific details of the circumstances leading to exposure highlight the need for additional efforts to define and characterize exposures to monkeypox in healthcare settings.

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Open Access on journal site

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