Persistence of Ebola Virus in Ocular Fluid during Convalescence
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Title
Persistence of Ebola Virus in Ocular Fluid during Convalescence
Subject
Description
Among the survivors of Ebola virus disease (EVD), complications that include uveitis can develop during convalescence, although the incidence and pathogenesis of EVD-associated uveitis are unknown.
This article was corrected in volume 372 on page 2469.
This article was corrected in volume 372 on page 2469.
Date
2015-06-18
Type
Citation
Varkey, J. B., J. G. Shantha, I. Crozier, C. S. Kraft, G. M. Lyon, A. K. Mehta, G. Kumar, J. R. Smith, M. H. Kainulainen, S. Whitmer, U. Stroher, T. M. Uyeki, B. S. Ribner and S. Yeh (2015). "Persistence of Ebola Virus in Ocular Fluid during Convalescence." N Engl J Med 372(25): 2423-2427.
Abstract
Among the survivors of Ebola virus disease (EVD), complications that include uveitis can develop during convalescence, although the incidence and pathogenesis of EVD-associated uveitis are unknown. We describe a patient who recovered from EVD and was subsequently found to have severe unilateral uveitis during convalescence. Viable Zaire ebolavirus (EBOV) was detected in aqueous humor 14 weeks after the onset of EVD and 9 weeks after the clearance of viremia.
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