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Browse Items (1475 total)
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Creator: Mok, Chris Ka Pun, Airu Zhu, Jingxian Zhao, Eric H. Y. Lau, Junxiang Wang, Zhao Chen, Zhen Zhuang, Yanqun Wang, Abeer N. Alshukairi, Salim A. Baharoon, Wenling Wang, Wenjie Tan, Weiwen Liang, Jamiu O. Oladipo, Ranawaka A. P. M. Perera, Sulyman A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-06
Description: Middle East respiratory syndrome (MERS) remains of global public health concern. Dromedary camels are the source of zoonotic infection. Over 70% of MERS coronavirus (MERS-CoV)-infected dromedaries are found in Africa but no zoonotic disease has been… -
Creator: Horby, Peter W., Marion Mafham, Jennifer L. Bell, Louise Linsell, Natalie Staplin, Jonathan Emberson, Adrian Palfreeman, Jason Raw, Einas Elmahi, Benjamin Prudon, Christopher Green, Simon Carley, David Chadwick, Matthew Davies, Matthew P. Wise, J.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-10-05
Description: Lopinavir–ritonavir has been proposed as a treatment for COVID-19 on the basis of in vitro activity, preclinical studies, and observational studies. Here, we report the results of a randomised trial to assess whether lopinavir–ritonavir improves… -
Creator: Anand, Shuchi, Maria Montez-Rath, Jialin Han, Julie Bozeman, Russell Kerschmann, Paul Beyer, Julie Parsonnet, and Glenn M. Chertow.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-25
Description: Many patients receiving dialysis in the USA share the socioeconomic characteristics of underserved communities, and undergo routine monthly laboratory testing, facilitating a practical, unbiased, and repeatable assessment of severe acute respiratory… -
Creator: Wang, Xu, Wenhui Wu, Peipei Song, and Jiangjiang He.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-20
Description: Coronavirus disease 19 (COVID-19) has become a pandemic around the world. With the explosive growth of confirmed cases, emergency medical supplies are facing global shortage, which restricts the treatment of seriously ill patients and protection of… -
Creator: Bax, Adriaan, Christina E. Bax, Valentyn Stadnytskyi, and Philip Anfinrud.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-11
Description: During a pandemic, identifying modes of transmission is paramount to devise effective and practical mitigation strategies. -
Creator: Furtado, Remo H. M., Otavio Berwanger, Henrique A. Fonseca, Thiago D. Corrêa, Leonardo R. Ferraz, Maura G. Lapa, Fernando G. Zampieri, Viviane C. Veiga, Luciano C. P. Azevedo, Regis G. Rosa, Renato D. Lopes, Alvaro Avezum, Airton L. O. Manoel, Felipe…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-08
Description: The efficacy and safety of azithromycin in the treatment of COVID-19 remain uncertain. We assessed whether adding azithromycin to standard of care, which included hydroxychloroquine, would improve clinical outcomes of patients admitted to the… -
Creator: Logunov, Denis Y., Inna V. Dolzhikova, Olga V. Zubkova, Amir I. Tukhvatullin, Dmitry V. Shcheblyakov, Alina S. Dzharullaeva, Daria M. Grousova, Alina S. Erokhova, Anna V. Kovyrshina, Andrei G. Botikov, Fatima M. Izhaeva, Olga Popova, Tatiana A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-21
Description: We developed a heterologous COVID-19 vaccine consisting of two components, a recombinant adenovirus type 26 (rAd26) vector and a recombinant adenovirus type 5 (rAd5) vector, both carrying the gene for severe acute respiratory syndrome coronavirus 2… -
Creator: Dugdale, C. M., S. E. Turbett, S. M. McCluskey, K. C. Zachary, E. S. Shenoy, A. L. Ciaranello, R. P. Walensky, E. S. Rosenberg, M. N. Anahtar, D. C. Hooper, and E. P. Hyle.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-24
Description: We describe an approach to the evaluation and isolation of hospitalized persons under investigation (PUIs) for COVID-19 at a large U.S. academic medical center. Only a small proportion (2.9%) of PUIs with one or more repeat SARS-CoV-2 nucleic acid… -
Creator: Davis, Carl W., Katherine J. L. Jackson, Megan M. McCausland, Jaime Darce, Cathy Chang, Susanne L. Linderman, Chakravarthy Chennareddy, Rebecca Gerkin, Shantoria J. Brown, Jens Wrammert, Aneesh K. Mehta, Wan Cheung Cheung, Scott D. Boyd, Edmund K.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-13
Description: A universal vaccine against influenza would ideally generate protective immune responses that are not only broadly reactive against multiple influenza strains, but also long-lasting. Because long-term serum antibody levels are maintained by bone… -
Creator: Mengfei Chen, Wenjuan Shen, Nicholas R. Rowan, Heather Kulaga, Alexander Hillel, Murugappan Ramanathan Jr, and Andrew P. Lane.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: ACE2 protein is expressed at high levels in the human olfactory epithelium relative to upper airway epithelial cells. This may explain COVID-19-associated olfactory dysfunction, while suggesting a SARS-CoV-2 reservoir site and potential intranasal…