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Browse Items (1475 total)
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Creator: Wongvibulsin, Shannon, Brian T. Garibaldi, Annukka A. R. Antar, Jiyang Wen, Mei-Cheng Wang, Amita Gupta, Robert Bollinger, Yanxun Xu, Kunbo Wang, Joshua F. Betz, John Muschelli, Karen Bandeen-Roche, Scott L. Zeger, and Matthew L. Robinson.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-03-02
Description: Predicting the clinical trajectory of individual patients hospitalized with coronavirus disease 2019 (COVID-19) is challenging but necessary to inform clinical care. The majority of COVID-19 prognostic tools use only data present upon admission and… -
Creator: Thompson, Elizabeth A., Katherine Cascino, Alvaro A. Ordonez, Weiqiang Zhou, Ajay Vaghasia, Anne Hamacher-Brady, Nathan R. Brady, Im-Hong Sun, Rulin Wang, Avi Z. Rosenberg, Michael Delannoy, Richard Rothman, Katherine Fenstermacher, Lauren Sauer,…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-26
Description: It is unclear why some SARS-CoV-2 patients readily resolve infection while others develop severe disease. By interrogating metabolic programs of immune cells in severe and recovered coronavirus disease 2019 (COVID-19) patients compared with other… -
Creator: CDC
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2021-01-08
Description: This report summarizes the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of the rVSVΔG-ZEBOV-GP Ebola vaccine (Ervebo) in the United States. The vaccine contains rice-derived recombinant human serum albumin and… -
Creator: Ella, Raches, Siddharth Reddy, Harsh Jogdand, Vamshi Sarangi, Brunda Ganneru, Sai Prasad, Dipankar Das, Dugyala Raju, Usha Praturi, Gajanan Sapkal, Pragya Yadav, Prabhakar Reddy, Savita Verma, Chandramani Singh, Sagar Vivek Redkar, Chandra Sekhar…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-03-08
Description: BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine (3 μg or 6 μg) formulated with a toll-like receptor 7/8 agonist molecule (IMDG) adsorbed to alum (Algel). We previously reported findings from a double-blind, multicentre, randomised, controlled… -
Creator: Liu, Yang, Jianying Liu, Hongjie Xia, Xianwen Zhang, Camila R. Fontes-Garfias, Kena A. Swanson, Hui Cai, Ritu Sarkar, Wei Chen, Mark Cutler, David Cooper, Scott C. Weaver, Alexander Muik, Ugur Sahin, Kathrin U. Jansen, Xuping Xie, Philip R.…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-03-08
Description: BNT162b2 is a nucleoside-modified RNA vaccine expressing the full-length prefusion spike glycoprotein (S) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In a randomized, placebo-controlled clinical trial involving approximately… -
Creator: PRINCIPLE Trial Collaborative Group
Subject: Research
Item Type: Publication
Date Last Updated: 2021-03-04
Description: Azithromycin, an antibiotic with potential antiviral and anti-inflammatory properties, has been used to treat COVID-19, but evidence from community randomised trials is lacking. We aimed to assess the effectiveness of azithromycin to treat suspected… -
Creator: Manisty, Charlotte, Ashley D. Otter, Thomas A. Treibel, Áine McKnight, Daniel M. Altmann, Timothy Brooks, Mahdad Noursadeghi, Rosemary J. Boyton, Amanda Semper, and James C. Moon.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: Rapid vaccine-induced population immunity is a key global strategy to control COVID-19. Vaccination programmes must maximise early impact, particularly with accelerated spread of new variants. -
Creator: Prendecki, Maria, Candice Clarke, Jonathan Brown, Alison Cox, Sarah Gleeson, Mary Guckian, Paul Randell, Alessia Dalla Pria, Liz Lightstone, Xiao-Ning Xu, Wendy Barclay, Stephen P. McAdoo, Peter Kelleher, and Michelle Willicombe.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: The rapid implementation of SARS-CoV-2 vaccination is now a global health-care priority. Successful phase 3 trial outcomes have been reported for numerous vaccines that induce robust humoral and cellular immune responses against the SARS-CoV-2 spike… -
Creator: Dagan, Noa, Noam Barda, Eldad Kepten, Oren Miron, Shay Perchik, Mark A. Katz, Miguel A. Hernán, Marc Lipsitch, Ben Reis, and Ran D. Balicer.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-24
Description: As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse populations in a noncontrolled setting. In this study, data from Israel’s… -
Creator: The RECOVERY Collaborative Group.
Subject: Research
Item Type: Publication
Date Last Updated: 2021-02-25
Description: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death.