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Navegar por los elementos (21 total)
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Autor: ACTT- Study Group
Tema: Treatment & Care
Tipo de elemento: Publicación
Fecha de actualización: 2022-05-23
Descripción: Baricitinib and dexamethasone have randomised trials supporting their use for the treatment of patients with COVID-19. We assessed the combination of baricitinib plus remdesivir versus dexamethasone plus remdesivir in preventing progression to… -
Autor: Corri B Levine, Sami Vasistha, Caroline Croyle Persson, LuAnn R Larson, Christopher J Kratochvil, Aneesh K Mehta, Lindsay J Hicks, Abigail E Lowe, Mark G Kortepeter, Lauren M Sauer
Tema: Emergency Management
Tipo de elemento: Publicación
Fecha de actualización: 2022-05-31
Descripción: The need for well-controlled clinical trials is fundamental to advancing medicine. Care should be taken to maintain high standards in trial design and conduct even during emergency medical events such as an infectious disease outbreak. In 2020,… -
Autor: Ella, Raches, Siddharth Reddy, Harsh Jogdand, Vamshi Sarangi, Brunda Ganneru, Sai Prasad, Dipankar Das, Dugyala Raju, Usha Praturi, Gajanan Sapkal, Pragya Yadav, Prabhakar Reddy, Savita Verma, Chandramani Singh, Sagar Vivek Redkar, Chandra Sekhar…
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2021-03-08
Descripción: BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine (3 μg or 6 μg) formulated with a toll-like receptor 7/8 agonist molecule (IMDG) adsorbed to alum (Algel). We previously reported findings from a double-blind, multicentre, randomised, controlled… -
Autor: WHO Solidarity Trial Consortium
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2020-12-02
Descripción: World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a — in patients hospitalized with coronavirus disease 2019 (Covid-19). -
Autor: Furtado, Remo H. M., Otavio Berwanger, Henrique A. Fonseca, Thiago D. Corrêa, Leonardo R. Ferraz, Maura G. Lapa, Fernando G. Zampieri, Viviane C. Veiga, Luciano C. P. Azevedo, Regis G. Rosa, Renato D. Lopes, Alvaro Avezum, Airton L. O. Manoel, Felipe…
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2020-09-08
Descripción: The efficacy and safety of azithromycin in the treatment of COVID-19 remain uncertain. We assessed whether adding azithromycin to standard of care, which included hydroxychloroquine, would improve clinical outcomes of patients admitted to the… -
Autor: Boulware, David R., Matthew F. Pullen, Ananta S. Bangdiwala, Katelyn A. Pastick, Sarah M. Lofgren, Elizabeth C. Okafor, Caleb P. Skipper, Alanna A. Nascene, Melanie R. Nicol, Mahsa Abassi, Nicole W. Engen, Matthew P. Cheng, Derek LaBar, Sylvain A.…
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2020-08-06
Descripción: This reports on a randomized, double-blind, placebo-controlled trial across the United States and parts of Canada testing hydroxychloroquine as postexposure prophylaxis. -
Autor: National Institute of Allergy and Infectious Diseases (NIAID)
Tema: Research
Tipo de elemento: Hipervínculo
Fecha de actualización: 2020-05-07
Descripción: This study is an adaptive, randomized, double-blind, placebo-controlled trial to evaluate the safety and efficacy of novel therapeutic agents in hospitalized adults diagnosed with COVID-19. The study is a multicenter trial that will be conducted in… -
Autor: the ACTT-1 Study Group Members
Tema: Treatment & Care
Tipo de elemento: Publicación
Fecha de actualización: 2020-05-22
Descripción: Discussing "a double-blind, randomized, placebo-controlled trial of intravenous remdesivir in adults hospitalized with Covid-19 with evidence of lower respiratory tract involvement." -
Autor: Dean, Natalie E., Pierre-Stéphane Gsell, Ron Brookmeyer, Forrest W. Crawford, Christl A. Donnelly, Susan S. Ellenberg, Thomas R. Fleming, M. Elizabeth Halloran, Peter Horby, Thomas Jaki, Philip R. Krause, Ira M. Longini, Sabue Mulangu, Jean-Jacques…
Tema: Emergency Management
Tipo de elemento: Publicación
Fecha de actualización: 2020-04-02
Descripción: Conducting trials of novel interventions during infectious disease emergencies, such as the ongoing Covid-19 pandemic, is increasingly recognized as important for determining the efficacy of potential vaccines and therapies. -
Autor: Fallah MP, Skrip LA.
Tema: Research
Tipo de elemento: Publicación
Fecha de actualización: 2019-01-24
Descripción: This article reviews the testing of Ebola therapies during the outbreak.