NETEC Resource Library

Development of a Pediatric Ebola Predictive Score, Sierra Leone

Contenu

Click for External Resource*


Click to read full article*


*The link above may share a zip file (.zip) hosted on repository.netecweb.org. Zip files will download automatically.
*All other links are external and will open in a new window. If you click an external link, you are leaving the NETEC site, and we do not maintain, review, or endorse these materials. See our terms of use.


Item Type

Publication

Terms of Use

By accessing these materials you are agreeing to our terms of use, which may be found here: Terms of Use.

Was this resource helpful?


Titre

Development of a Pediatric Ebola Predictive Score, Sierra Leone

Sujet

Description

We compared children who were positive for Ebola virus disease (EVD) with those who were negative to derive a pediatric EVD predictor (PEP) score.

Date

2018-02

Citer ce document

Fitzgerald, F., Wing, K., Naveed, A., Gbessay, M., Ross, J., Checchi, F....Yeung, S. 2018. Development of a Pediatric Ebola Predictive Score, Sierra Leone. Emerging Infectious Diseases, 24(2), 311-319. https://dx.doi.org/10.3201/eid2402.171018.

Résumé

We compared children who were positive for Ebola virus disease (EVD) with those who were negative to derive a pediatric EVD predictor (PEP) score. We collected data on all children <13 years of age admitted to 11 Ebola holding units in Sierra Leone during August 2014-March 2015 and performed multivariable logistic regression. Among 1,054 children, 309 (29%) were EVD positive and 697 (66%) EVD negative, with 48 (5%) missing. Contact history, conjunctivitis, and age were the strongest positive predictors for EVD. The PEP score had an area under receiver operating characteristics curve of 0.80. A PEP score of 7/10 was 92% specific and 44% sensitive; 3/10 was 30% specific, 94% sensitive. The PEP score could correctly classify 79%-90% of children and could be used to facilitate triage into risk categories, depending on the sensitivity or specificity required.

Accessibilité

Free online.

Collection

Related Resource Topic Exhibits