COVID-19 and multisystem inflammatory syndrome in children and adolescents
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Título
COVID-19 and multisystem inflammatory syndrome in children and adolescents
Materia
Descripción
As severe acute respiratory syndrome coronavirus 2 continues to spread worldwide, there have been increasing reports from Europe, North America, Asia, and Latin America describing children and adolescents with COVID-19-associated multisystem inflammatory conditions.
A response to this article was published:
A response to this article was published:
- Schwartz, Michael. 2020. "MIS-C: post-infectious syndrome or persistent infection?" The Lancet Infectious Diseases.
Fecha
2020-08-17
Tipo
Citación
Jiang, Li, Kun Tang, Mike Levin, Omar Irfan, Shaun K. Morris, Karen Wilson, Jonathan D. Klein, and Zulfiqar A. Bhutta. 2020. "COVID-19 and multisystem inflammatory syndrome in children and adolescents." The Lancet Infectious Diseases.
Resumen
Summary
As severe acute respiratory syndrome coronavirus 2 continues to spread worldwide, there have been increasing reports from Europe, North America, Asia, and Latin America describing children and adolescents with COVID-19-associated multisystem inflammatory conditions. However, the association between multisystem inflammatory syndrome in children and COVID-19 is still unknown. We review the epidemiology, causes, clinical features, and current treatment protocols for multisystem inflammatory syndrome in children and adolescents associated with COVID-19. We also discuss the possible underlying pathophysiological mechanisms for COVID-19-induced inflammatory processes, which can lead to organ damage in paediatric patients who are severely ill. These insights provide evidence for the need to develop a clear case definition and treatment protocol for this new condition and also shed light on future therapeutic interventions and the potential for vaccine development.
Translations
For the French, Chinese, Arabic, Spanish and Russian translations of the abstract see Supplementary Materials section.
Accesibilidad
Free online on Lancet site.
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