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Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever

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Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Feverhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682919/pdf/nihms904566.pdf

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Publicación

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Título

Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever

Descripción

Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir.

Fecha

2017-09-01

Citación

Raabe, V. N., G. Kann, B. S. Ribner, A. Morales, J. B. Varkey, A. K. Mehta, G. M. Lyon, S. Vanairsdale, K. Faber, S. Becker, M. Eickmann, T. Strecker, S. Brown, K. Patel, P. De Leuw, G. Schuettfort, C. Stephan, H. Rabenau, J. D. Klena, P. E. Rollin, A. McElroy, U. Stroher, S. Nichol, C. S. Kraft, T. Wolf and U. Emory Serious Communicable Diseases (2017). "Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever." Clin Infect Dis 65(5): 855-859.

Resumen

Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir. Both patients survived but developed transaminitis and had prolonged detectable virus RNA in blood and semen, suggesting that the possibility of sexual transmission of Lassa virus should be considered.

Accesibilidad

free online - Pubmed Central

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