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The Use of Convalescent Plasma Therapy and Remdesivir in the Successful Management of a Critically Ill Obstetric Patient With Novel Coronavirus 2019 Infection: A Case Report

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Title

The Use of Convalescent Plasma Therapy and Remdesivir in the Successful Management of a Critically Ill Obstetric Patient With Novel Coronavirus 2019 Infection: A Case Report

Description

Remdesivir is a novel therapeutic with known activity against SARS CoV-2 and related coronaviruses. Remdesivir, as well as convalescent plasma therapy, are currently under investigation as potential therapies for patients with Coronavirus Disease 19 (COVID-19).

Date

2020-05-16

Citation

Anderson, Jonathon, Jordan Schauer, Suzanne Bryant, and Cornelia R. Graves. 2020. "The use of convalescent plasma therapy and remdesivir in the successful management of a critically ill obstetric patient with novel coronavirus 2019 infection: A case report." Case Reports in Women's Health:e00221.

Abstract

Summary

Remdesivir is a novel therapeutic with known activity against SARS CoV-2 and related coronaviruses. Remdesivir, as well as convalescent plasma therapy, are currently under investigation as potential therapies for patients with Coronavirus Disease 19 (COVID-19). In this case report we summarize the use of convalescent plasma therapy and then remdesivir as a late addition in the treatment of a critically ill obstetric patient with COVID-19. The patient subsequently improved, was extubated 5 days after initiation of remdesivir, was transitioned to room air 24 h later, and discharged at the completion of remdesivir therapy.

Keywords

Remdesivir
Convalescent plasma
COVID-19
SARS CoV-2
Coronavirus
Pregnancy

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Free online

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