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Browse Items (55 total)

  • Tags: Research

Creator: Wyllie, Anne L., John Fournier, Arnau Casanovas-Massana, Melissa Campbell, Maria Tokuyama, Pavithra Vijayakumar, Joshua L. Warren, Bertie Geng, M. Catherine Muenker, Adam J. Moore, Chantal B. F. Vogels, Mary E. Petrone, Isabel M. Ott, Peiwen Lu,…
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-09-24
Description: Rapid and accurate diagnostic tests are essential for controlling the ongoing Covid-19 pandemic. Although the current standard involves testing of nasopharyngeal swab specimens by quantitative reverse-transcriptase polymerase chain reaction (RT-qPCR)…

Creator: Ehre, Camille.
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-09-03
Description: In a laboratory setting, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was inoculated into human bronchial epithelial cells.

Creator: Solomon, Isaac H., Erica Normandin, Shamik Bhattacharyya, Shibani S. Mukerji, Kiana Keller, Ahya S. Ali, Gordon Adams, Jason L. Hornick, Robert F. Padera, and Pardis Sabeti.
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2020-09-03
Description: Neurologic symptoms, including headache, altered mental status, and anosmia, occur in many patients with Covid-19.

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Creator: Logunov, Denis Y., Inna V. Dolzhikova, Olga V. Zubkova, Amir I. Tukhvatullin, Dmitry V. Shcheblyakov, Alina S. Dzharullaeva, Daria M. Grousova, Alina S. Erokhova, Anna V. Kovyrshina, Andrei G. Botikov, Fatima M. Izhaeva, Olga Popova, Tatiana A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-21
Description: We developed a heterologous COVID-19 vaccine consisting of two components, a recombinant adenovirus type 26 (rAd26) vector and a recombinant adenovirus type 5 (rAd5) vector, both carrying the gene for severe acute respiratory syndrome coronavirus 2…

Creator: Dugdale, C. M., S. E. Turbett, S. M. McCluskey, K. C. Zachary, E. S. Shenoy, A. L. Ciaranello, R. P. Walensky, E. S. Rosenberg, M. N. Anahtar, D. C. Hooper, and E. P. Hyle.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-24
Description: We describe an approach to the evaluation and isolation of hospitalized persons under investigation (PUIs) for COVID-19 at a large U.S. academic medical center. Only a small proportion (2.9%) of PUIs with one or more repeat SARS-CoV-2 nucleic acid…

Creator: Suthar, M. S., M. G. Zimmerman, R. C. Kauffman, G. Mantus, S. L. Linderman, W. H. Hudson, A. Vanderheiden, L. Nyhoff, C. W. Davis, O. Adekunle, M. Affer, M. Sherman, S. Reynolds, H. P. Verkerke, D. N. Alter, J. Guarner, J. Bryksin, M. C. Horwath, C.…
Subject: Laboratory
Item Type: Publication
Date Last Updated: 2020-06-23
Description: SARS-CoV-2, the virus responsible for COVID-19, is causing a devastating worldwide pandemic, and there is a pressing need to understand the development, specificity, and neutralizing potency of humoral immune responses during acute infection. We…

Creator: Sakurai, Aki, Toshiharu Sasaki, Shigeo Kato, Masamichi Hayashi, Sei-ichiro Tsuzuki, Takuma Ishihara, Mitsunaga Iwata, Zenichi Morise, and Yohei Doi.
Subject: Infection Control
Item Type: Publication
Date Last Updated: 2020-08-27
Description: Information on the natural history of asymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains scarce.

Creator: Davis, Carl W., Katherine J. L. Jackson, Megan M. McCausland, Jaime Darce, Cathy Chang, Susanne L. Linderman, Chakravarthy Chennareddy, Rebecca Gerkin, Shantoria J. Brown, Jens Wrammert, Aneesh K. Mehta, Wan Cheung Cheung, Scott D. Boyd, Edmund K.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-13
Description: A universal vaccine against influenza would ideally generate protective immune responses that are not only broadly reactive against multiple influenza strains, but also long-lasting. Because long-term serum antibody levels are maintained by bone…

Creator: Mengfei Chen, Wenjuan Shen, Nicholas R. Rowan, Heather Kulaga, Alexander Hillel, Murugappan Ramanathan Jr, and Andrew P. Lane.
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: ACE2 protein is expressed at high levels in the human olfactory epithelium relative to upper airway epithelial cells. This may explain COVID-19-associated olfactory dysfunction, while suggesting a SARS-CoV-2 reservoir site and potential intranasal…

Creator: Young, Barnaby E., Siew-Wai Fong, Yi-Hao Chan, Tze-Minn Mak, Li Wei Ang, Danielle E. Anderson, Cheryl Yi-Pin Lee, Siti Naqiah Amrun, Bernett Lee, Yun Shan Goh, Yvonne C. F. Su, Wycliffe E. Wei, Shirin Kalimuddin, Louis Yi Ann Chai, Surinder Pada,…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-18
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with a 382-nucleotide deletion (∆382) in the open reading frame 8 (ORF8) region of the genome have been detected in Singapore and other countries. We investigated the effect of…