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Browse Items (21 total)
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Creator: Mbala-Kingebeni P, Aziza A, Di Paola N, Wiley MR, Makiala-Mandanda S, Caviness K, Pratt CB, Ladner JT, Kugelman JR, Prieto K, Chitty JA, Larson PA, Beitzel B, Ayouba A, Vidal N, Karhemere S, Diop M, Diagne MM, Faye M, Faye O, Aruna A, Nsio J, Mulangu…
Subject: Research
Item Type: Publication
Date Last Updated: 2019-04-15
Description: The real-time generation of information about pathogen genomes has become a vital goal for transmission analysis and characterisation in rapid outbreak responses. In response to the recently established genomic capacity in the Democratic Republic of… -
Creator: Fallah MP, Skrip LA.
Subject: Research
Item Type: Publication
Date Last Updated: 2019-01-24
Description: This article reviews the testing of Ebola therapies during the outbreak. -
Creator: Dean, Natalie E., Pierre-Stéphane Gsell, Ron Brookmeyer, Forrest W. Crawford, Christl A. Donnelly, Susan S. Ellenberg, Thomas R. Fleming, M. Elizabeth Halloran, Peter Horby, Thomas Jaki, Philip R. Krause, Ira M. Longini, Sabue Mulangu, Jean-Jacques…
Subject: Emergency Management
Item Type: Publication
Date Last Updated: 2020-04-02
Description: Conducting trials of novel interventions during infectious disease emergencies, such as the ongoing Covid-19 pandemic, is increasingly recognized as important for determining the efficacy of potential vaccines and therapies. -
Creator: the ACTT-1 Study Group Members
Subject: Treatment & Care
Item Type: Publication
Date Last Updated: 2020-05-22
Description: Discussing "a double-blind, randomized, placebo-controlled trial of intravenous remdesivir in adults hospitalized with Covid-19 with evidence of lower respiratory tract involvement." -
Creator: National Institute of Allergy and Infectious Diseases (NIAID)
Subject: Research
Item Type: Hyperlink
Date Last Updated: 2020-05-07
Description: This study is an adaptive, randomized, double-blind, placebo-controlled trial to evaluate the safety and efficacy of novel therapeutic agents in hospitalized adults diagnosed with COVID-19. The study is a multicenter trial that will be conducted in… -
Creator: Boulware, David R., Matthew F. Pullen, Ananta S. Bangdiwala, Katelyn A. Pastick, Sarah M. Lofgren, Elizabeth C. Okafor, Caleb P. Skipper, Alanna A. Nascene, Melanie R. Nicol, Mahsa Abassi, Nicole W. Engen, Matthew P. Cheng, Derek LaBar, Sylvain A.…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-08-06
Description: This reports on a randomized, double-blind, placebo-controlled trial across the United States and parts of Canada testing hydroxychloroquine as postexposure prophylaxis. -
Creator: Furtado, Remo H. M., Otavio Berwanger, Henrique A. Fonseca, Thiago D. Corrêa, Leonardo R. Ferraz, Maura G. Lapa, Fernando G. Zampieri, Viviane C. Veiga, Luciano C. P. Azevedo, Regis G. Rosa, Renato D. Lopes, Alvaro Avezum, Airton L. O. Manoel, Felipe…
Subject: Research
Item Type: Publication
Date Last Updated: 2020-09-08
Description: The efficacy and safety of azithromycin in the treatment of COVID-19 remain uncertain. We assessed whether adding azithromycin to standard of care, which included hydroxychloroquine, would improve clinical outcomes of patients admitted to the… -
Creator: WHO Solidarity Trial Consortium
Subject: Research
Item Type: Publication
Date Last Updated: 2020-12-02
Description: World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a — in patients hospitalized with coronavirus disease 2019 (Covid-19). -
Creator: Ella, Raches, Siddharth Reddy, Harsh Jogdand, Vamshi Sarangi, Brunda Ganneru, Sai Prasad, Dipankar Das, Dugyala Raju, Usha Praturi, Gajanan Sapkal, Pragya Yadav, Prabhakar Reddy, Savita Verma, Chandramani Singh, Sagar Vivek Redkar, Chandra Sekhar…
Subject: Research
Item Type: Publication
Date Last Updated: 2021-03-08
Description: BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine (3 μg or 6 μg) formulated with a toll-like receptor 7/8 agonist molecule (IMDG) adsorbed to alum (Algel). We previously reported findings from a double-blind, multicentre, randomised, controlled… -
Creator: Corri B Levine, Sami Vasistha, Caroline Croyle Persson, LuAnn R Larson, Christopher J Kratochvil, Aneesh K Mehta, Lindsay J Hicks, Abigail E Lowe, Mark G Kortepeter, Lauren M Sauer
Subject: Emergency Management
Item Type: Publication
Date Last Updated: 2022-05-31
Description: The need for well-controlled clinical trials is fundamental to advancing medicine. Care should be taken to maintain high standards in trial design and conduct even during emergency medical events such as an infectious disease outbreak. In 2020,…